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University of Groningen Contributions to the study of the complement system in IgA nephropathy and dialysis Albuquerque Pereira Oliveira, António Bernardo

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University of Groningen

Contributions to the study of the complement system in IgA nephropathy and dialysis

Albuquerque Pereira Oliveira, António Bernardo

DOI:

10.33612/diss.154427061

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Albuquerque Pereira Oliveira, A. B. (2021). Contributions to the study of the complement system in IgA nephropathy and dialysis. University of Groningen. https://doi.org/10.33612/diss.154427061

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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TABLE OF CONTENTS

Chapter 1 General Introduction 8

PART A – The Complement System in IgA Nephropathy

Chapter 2 Combined C4d and CD3 predicts IgA Nephropathy progression

Clinical and Experimental Immunology, 2015

22 Chapter 3 Arteriolar C4d in IgA Nephropathy: a cohort study

American Journal of Kidney Diseases, 2020 40

PART B – The Complement System in Dialysis

Chapter 4 The complement system in dialysis: a forgotten story?

Frontiers in Immunology, 2018 66

Chapter 5 Intradialytic complement activation precedes the development of cardiovascular events in hemodialysis patients.

Frontiers in Immunology, 2018

96 Chapter 6 Administration of intravenous iron preparations induces

complement activation in-vivo. Frontiers in Immunology, 2019

120 Chapter 7 Soluble CD59 in peritoneal dialysis: a potential biomarker for

peritoneal membrane function. Journal of Nephrology, 2020

140 Chapter 8 Peritoneal dialysis independently induces local and systemic

complement activation via distinct pathways. In preparation

164

Chapter 9 Summary, discussion and future perspectives 198

Appendices Samenvatting en Discussie Sumário e Discussão Acknowledgments About the author

210 218 226 229

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