University of Groningen
Ambulatory assessment of human circadian phase and related sleep disorders from heart
rate variability and other non-invasive physiological measurements
Gil Ponce, Enrique
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Publication date: 2017
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Gil Ponce, E. (2017). Ambulatory assessment of human circadian phase and related sleep disorders from heart rate variability and other non-invasive physiological measurements. University of Groningen.
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IST OF TABLES
Table 1.1 Summary of reported results for 4 circadian phase estimation models using non-invasive data in ambulatory conditions. Models are sorted by accuracy
(standard deviation of the error). ... 32
Table 2.1 Average error (bias) defined as the difference between the measured DLMO and the predicted DLMO, and standard deviation of the error (SD error) for the ARMAX models using activity, RR intervals, and light. Pearson’s R coefficient indicating a significant correlation (p<0.05) are shown in bold. ... 50
Table 4.1 Summary of results ... 72
Table 5.1 Subject characteristics of 16 subjects with valid PPG and ECG data. ... 85
Table 5.2 Performance of original models on an older subject population. The models were applied on the ECG signals of all subjects (N=29) and shown in A. The subset of subject which in addition to having usable ECG signals also had usable PPG signals (N=16) are shown in B. The various models represent all possible input signal combinations: RR Intervals (R), activity levels (A), and light exposure (L). ... 86
Table 5.3 Performance of the models based on PPG signal from a wrist-worn optical heart rate sensor (N=16). ... 87
Table 5.4 Testing of retrained models based on ECG data targeted at the older subject population. ... 87
Table 5.5 Testing of retrained models based on PPG data targeted at the older subject population. ... 88
Table 5.6 Performance of newly ECG-trained models from older adults (N=8) when applied to PPG data from a separate sample of the older adult population (N=8). ... 88
Table 6.1 Subject characteristics and questionnaire outcomes. ... 98
Table 6.2 Sleep statistics of the SOI patients. ... 99
Table 6.3 Distribution of different sleep stages in SOI patients. ... 100
Table 6.4 Summary of studies reporting the timing of the SDNN maximum in healthy subjects... 102
Table 7.1 Demographics ... 115
Table 7.2 Accuracy of all model configurations ranked by accuracy. ... 116
Table 7.3 Differences in phase angles of entrainment (hours) between healthy subjects and sleep onset insomnia patients... 117
