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University of Groningen

Functioning beyond pediatric burns

Akkerman, Moniek

DOI:

10.33612/diss.111357428

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date:

2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Akkerman, M. (2020). Functioning beyond pediatric burns: physical activity, fatigue, and exercise capacity

up to 5 years post burn. University of Groningen. https://doi.org/10.33612/diss.111357428

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Functioning beyond pediatric burns

physical activity, fatigue, and exercise capacity

up to 5 years post burn

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This thesis is a product of a close collaboration between:

• The Association of Dutch Burn Centers, Burn Center Groningen, Martini Hospital Groningen

• The Center for Human Movement Sciences, University of Groningen, University Medical Center Groningen • The Child Development and Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht The studies regarding pediatric burns were financially supported by the Dutch Burns Foundation.

PhD training was facilitated by the Research Institute School of Health Sciences (SHARE), part of the Graduate School for Medical Sciences Groningen.

The printing of this thesis was financially supported by: • Stichting Brandwonden Research Instituut / HUMECA • ProCare B.V.

• Lode B.V.

• The Dutch Burns Foundation

• Research Institute School of Health Research (SHARE) • University of Groningen

• University Medical Center Groningen

Cover photo & editing: Stefan Schipper – www.stefanschipper.nl Layout: XML 2 Publish – www.xml2publish.com Printed by: Gildeprint – www.gildeprint.nl ISBN printed version: 978-94-034-2292-3

ISBN digital version: 978-94-034-2291-6

Paranimphs: Janneke Akkerman & Yvonne Dikkema Copyright © Moniek Akkerman, 2019

All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without written permis-sion from the author.

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Functioning beyond pediatric burns

physical activity, fatigue, and exercise capacity

up to 5 years post burn

PhD thesis

to obtain the degree of PhD at the

University of Groningen

on the authority of the

Rector Magnificus Prof. C. Wijmenga

and in accordance with

the decision by the College of Deans.

This thesis will be defended in public on

Tuesday 21 January 2020 at 11.00 hours

by

Moniek Akkerman

born on 13 February 1986

in Zevenaar

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Supervisor

Prof. dr. L.H.V. van der Woude

Co-supervisors

Dr. L.J. Mouton

Dr. M.K. Nieuwenhuis

Assessment committee

Prof. dr. C. Veenhof

Prof. dr. E. Middelkoop

Prof. dr. K.A.P.M Lemmink

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TAble oF ConTenTs

Chapter 1 General introduction

7

Chapter 2 Physical activity and sedentary behavior following pediatric burns

– a preliminary investigation using objective activity monitoring

21

Chapter 3

Perceived fatigue following pediatric burns

43

Chapter 4 The oxygen uptake efficiency slope: what do we know?

63

Chapter 5

Oxygen uptake efficiency slope in healthy children

91

Chapter 6 Predictability of exercise capacity following pediatric burns

– a preliminary investigation

105

Chapter 7 General discussion

127

Appendix

Summary in English

146

Nederlandse samenvatting

150

Cover story

155

Dankwoord

157

About the author

164

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