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Academic year: 2022

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(1)

Year review

Regenerative Medicine Utrecht

2020

(2)

2020 was a bizarre year.

The Corona pandemic had a big impact on us.

The RMU-center was closed for 8 Weeks.

Promotions and conferences were cancelled and researchers were forced to work at home

Corona

(3)

Fortunately, the research was restarted before the summer.

Corona

And tools became available to hold meetings online

0%

25%

50%

75%

100%

access RMCU

The building was made corona-proof.

(4)

And despite everything,

there were so many reasons to be proud

We had new (associate) professors

Several awards & grants

We had on-line seminars and events

We did education and training

We had a lot of new doctors

And we were in news a lot

And it's been 5 years since the RMCU opened

Many reasons to be proud

(5)

Our new professors

Harold Brommer

Professor

Heelkunde van het paard

Tina Vermonden

Professor

Biomaterials for Drug Delivery and Regenerative Medicine

(6)

Our new Associate Professors

Bart Spee

Peter de Keizer Niels van der Kaaij

Our new PI

Saber Amin Yavari

(7)

AWARDS

Laura Creemers

Reviewer Award Acta Biomaterialia

Pamela Carpendale

Best presentation ISCOMS Congress

Arif Ibrahim Ardisasmita

Best master thesis 2020

Paulina Nunez Bernal

Best oral presentation at the Veterinary Science day

Merle Maas-Krebber

Best poster at MDR2020

We received lots of

(8)

Surgical Spine

Center of Excellence

The multidisciplinary expertise in the field of spinal surgery at UMC Utrecht has been officially recognized by the international organization EUROSPINE.

The appointment as a "Surgical Spine Center of Excellence" applies for the

next four years

AWARDS

We received lots of

(9)

AWARDS

Prof. René Castelein

awarded as Knight of the Orde van de Nederlandse Leeuw

On September 4th, prof. René Castelein said goodbye to UMC Utrecht

(10)

Cora Nijboer

EU-grant PREMSTEM consortium

To develop new therapy to treat brain damage in premature babies

Eva van Rooij

NWO Vici

This grant will enable her to develop an innovative line of research and expand her research group in

the coming five years.

Laura Creemers

Marie Curie H2020 ITN grant

Together with Dr. Jacqueline Alblas and Dr. João Garcia, she will be the linking pin of a European network of 15 PhD students that will work on non-

viral gene therapy for the treatment of osteoarthritis and intervertebral disc disease

GRANTS

(11)

Riccardo Levato

NOW Idea Generator Grant

to develop and adapt the ultra-fast (volumetric) 3D bioprinting technology for the treatment of

osteoarthritis

Jeffrey Beekman

Health Holland

SARS-CoV-2 research

Moyo Kruijt

Open Technology Programme Grant

A novel Spinal Spring Distraction System: Guiding growth to correct Early Onset Scoliosis (SpiDi)

Saber Amin Yavari

NWO Demonstrator Grant

New Treatment of Hip Dysplasia

GRANTS

(12)

Riccardo Levato

ERC starting grant

to develop a 3D printer that can reproduce parts of the human body, including living cells,

within minutes

Miquel Dias Castilho

HHT-HiTmaT 2020 grant

Advaessel: Advanced materials processing and design for regenerating blood vessels

Madelon Maurice

LKB1 gene mutations in colorectal cancer KWF

development and growth

GRANTS

(13)

Riccardo Levato

Horizon 2020 Grant

ENLIGHT: New Bioprinting Method

Karin Gerritsen

Horizon 2020 grant

First in man Trial improve peritoneal dialyses

Miguel Dias Castilho

NWO XS grant

Recapitulating bone development through 3D Printing in Suspension Baths - RePrint

GRANTS

(14)

Prof.

Howard J.

Hillstrom,

Motion Analysis Laboratory, New

York

Dr. Liliang Ouyang,

Imperial College London

RMU SEMINARS

All these external speakers

found their (online) way to RMCU to inspire us!

Prof. Dr.

Daniel J.

Kelly,

Trinity College Dublin

Prof.

Michele de Luca,

University of Modena and Reggio Emila

Prof.

Graziella Pellegrini,

University of Modena and Reggio Emila

Dr Marc Bohner,

RMS Foundation, Switzerland

Dr. Ruben van Boxtel,

Princess Maxima Center Utrecht

(15)

RMU Valorisation Café –

How to create impact with your research 13 July

TPI Helpathon: animal-free innovations 18-19 June

We had various

to attend!

(online)E VENTS

RegMed XB Annual Meeting held in Railway Museum

4-5 March

(16)

Utrecht Life Sciences Facility

Event

October 27th

On line

Materials-driven regeneration

meeting

November 19-20

On line

(online)E VENTS

(17)

Launch event alliance TU/e, WUR, UU, UMC

Utrecht

December 2

On line Towards Animal-

Free Science: U- AIM webinar November 24 &

December 15

On line

(online)EVENTS

(18)

Opening centraal 3D Lab

EVENTS

(19)

Education & Training

This year all courses were modified to a hybrid format!

Master course

Regenerative Medicine and Technology Intro Course Biofabrication Introductory course

Bachelor course

Regenerative Medicine

Stem Cells and Regenerative Medicine Short courses

Fundamentals of Biofabrication ONLINE Vascularized tissue engineering ONLINE

16 PhD students started their research project

65 students did their internship at the RMCU

PhD Courses Intro to Stem Cells

Intro to Regenerative medicine

Tissue engineering of the gastrointestinal system Cardiorenal RM

Musculoskeletal RM Perspectives in RM Enabling Technologies From Bench to Bedside

We got 22 new Doctors!

(20)

Education & Training

Educational qualification BKO

Merle Krebber

Edward Nieuwenhuis Eva van Rooij

Onno Kranenburg Daniel Saris

achieved their Education Qualification (BKO) congrats

(21)

ON LINE

3D Printing andBiofabrication by Dr. Riccardo Levato &

Prof. Jos Malda

Education & Training

(22)

Stephanie Veraa

Imaging of the Equine Neck

Lies Fliervoet

Hydrogels releasing polymeric nanoparticles for local delivery of nucleic acids

Laura Louzao Martinez

The extracellular matrix and angiogenesis - two aspects that define cardiovascular health and disease

Nabila Boukelmoune

Nasal mesenchymal stem cell treatment for the repair of chemotherapy-induced neurotoxicities: let the trojan horse in!

We got new Doctors!

(23)

Barbara Klotz

Engineering gelatin-based

biomatrices for pre-vascularisation of bone analogues

Mario Hevesi

Biologic Joint Preservation

Chella Hagmeijer

Patient centered strategies to prevent

osteoarthritis after meniscus injury Victor van de Graaf

Biologic Joint Preservation

Joep Eding

RNA targets in cardiac disease

We got new Doctors!

(24)

Iris Otto

From cell to society: Bioengineering auricular cartilage for ear reconstruction

Paweena Diloksumpan

The use of converging biofabrication

techniques to address nature's complexity in joint repair

Gitte Berkers

Personalizing CFTR modulator therapies

We got new Doctors!

Delphi Coppens

Regulating gene and cell based therapies as medicinal products

Joep Beumer

Constructing roadmaps towards functional cell types using

organoids

(25)

Yorick Post

Modeling Vertebrate Adult Stem Cells And Their Progeny

Jiayi Pei

Multi-omics dissection of acquired and inherited heart failure

We got new Doctors!

Joao Marques Garcia

Tools and Technologies for

Cartilage Repair Alessia Longoni

Endochondral bone regeneration:

Stepping stones towards clinical translation

(26)

Irina Mancini

Translation Of (Osteo)chondral Regenerative Strategies

Mylene de Rijter

Diarthrodial joint resurfacing: Multi-scale biofabrication of mechanically stable implants

We got new Doctors!

Iris Pennings

Bioengineering of pre-vascularized bone tissue analogues Laying the basis for a perfusable hierarchical vascular therapies

Casper van der ven

ADDING A DIMENSION: Engineering a 3D heart valve disease model and timed release of RNA therapeutics

(27)

We were in the News a lot !

(28)

We were in the News a lot !

A regenerative solution for spinal fusions

When pharmacology and theoretical physics meet

New miniature system to study kidney and intestine function Utrecht working group for animal- free innovations in science

(29)

We were in the News a lot !

Curing genetic disease in human stem cells

(30)

We also went !

(31)

it's been 5 years since the RMCU opened

Our Goal:

Strength through sharing knowledge, infrastructure and networks

Connects people and resources

Facilitates and organizes knowledge exchange

Offers high-tech facilities

Provides access to core facilities

Stimulates valorisation

Bio technical Bio

medical Clinical

Regenerative Medicine Center

Utrecht

2015-2020:

in 5 years we have grown considerably (almost doubled)

From 190 to 315 people

From 109 to 210 FTE

From 5 UMCU division to 5 UMCU + 6 UU-Veterinary Sciences groups

71

37

97 45

13

1613 23

Function

studenten technicians PhD studenten senior researchers clinical researcher PI/Professor administration visiting

(32)

instead of a grand live event, we celebrated our RMCU 5 year

existence online

(33)

No Labcleaning and TGIF-drinks

x

but social and fun events online

(34)
(35)

We look back at a strange and bizarre year, but despite everything a very successful year.

Special thanks to all researchers and students in the RM Utrecht community!

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