Bouncing back : trauma and the HPA-axis in healthy adults
Klaassens, E.R.
Citation
Klaassens, E. R. (2010, November 30). Bouncing back : trauma and the HPA-axis in healthy adults. Retrieved from https://hdl.handle.net/1887/16190
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded from: https://hdl.handle.net/1887/16190
Note: To cite this publication please use the final published version (if
applicable).
Curriculum Vitae
174
175 Curriculum Vitae
Curriculum Vitae
Ellen Renée Klaassens was born on June 13th,1962 in Utrecht, the Netherlands.
She received her secondary education at the Praedinius Gymnasium in Groningen (1974-1976), the Willem de Zwijger College in Bussum (1976- 1977) and the Gemeentelijk Gynmasium in Hilversum (1977-1981). In 1981 she went to live in Calgary, Alberta, Canada where she graduated with Honours from Henry Wisewood Sr. Highschool. Back in the Netherlands she studied Human Nutrition and Dietetics in The Hague from 1982-1986.
In 1996 she enrolled at Leiden University to study Psychology where she graduated Cum Laude in Clinical and Health Psychology in September 2004.
Also in September 2004 she started the work described in this dissertation at the Leiden University Medical Center (LUMC), department of Psychiatry (promotor Prof.dr. F.G. Zitman). In February 2008 she started working as a psychologist and researcher at Riagg Rijnmond, a regional community mental health care center located in Rotterdam and Schiedam, where she continues to work today. In the meantime she worked on completion of this dissertation.
In September 2010 she started a 2-years post-graduate training at Riagg Rijnmond to become a registered GZ-psychologist.
Publications
178
179 Publications
Publications
1. Klaassens ER, Giltay ER, Cuijpers P, van Veen T, Zitman FG. Adulthood trauma and cortisol in healthy subjects and PTSD patients: a meta-analysis.
Submitted for publication
2. Kooiman CG, Klaassens ER, van Heloma Lugt JQ, Kamperman AM. Factor structure, reliability and validity of the Dutch translation of the Experiences in Close Relationships-revised (ECR-r) in an outpatient mental health sample. Submitted for publication
3. Veen G, Giltay EJ, DeRijk RH, van Vliet IM, Klaassens ER, van Pelt J, Zitman FG. C-reactive protein polymorphisms are associated with plasma C-reactive protein levels and the cortisol awakening response in basal conditions. In press
4. Klaassens ER, Giltay EJ, van Veen T, Veen G, Zitman FG. Trauma exposure in relation to basal salivary cortisol and the hormone response to the dexamethasone/CRH test in male railway employees without lifetime psychopathology. Psychoneuroendocrinology 2010;35:878-886.
5. Klaassens ER, van Veen T., Giltay EJ, Rinne T, van Pelt J, Zitman FG. Trauma exposure and hypothalamic-pituitary- adrenal axis functioning in mentally healthy Dutch peacekeeping veterans, 10-25 years after deployment. J Trauma Stress 2010;23:124-31.
6. Klaassens ER, van Noorden MS, Giltay EJ, van Pelt J, van Veen T, Zitman FG. Effects of childhood trauma on HPA-axis reactivity in women free of lifetime psychopathology. Prog Neuro-Psychopharmacol Biol Psychiatry 2009;33:889-94.
7. Klaassens ER, van Veen T, Weerts JMP, Zitman FG. Mental health of Dutch Peacekeeping Veterans 10-25 years after deployment. Eur Psychiatry 2008;23:486-90.
8. Klaassens ER, van Veen T, Zitman FG. Does trauma cause lasting changes in HPA-axis functioning in healthy individuals? In: de Kloet ER. Progr Brain:
Stress Hormones and Post Traumatic Stress Disorder Basic Studies and Clinical Perspectives. Volume 167 ed. Elsevier; 2008:273-5.
Abbreviations
182
183 Abbreviations
Abbreviations
ACTH adrenocorticotropic hormone ANOVA analysis of variance
ANS autonomic nervous system
AUC Area Under the Curve
AUCg Area Under the Curve with respect to ground
AVP arginine vasopressin
BMI body mass index
BSI Brief Symptom Inventory
CAR cortisol awakening response
CES combat exposure scale
CI confidence interval
CRH corticotropin-releasing hormone
CTQ-SF Childhood Trauma Questionnaire-Short Form
Dex/CRH test dexamethasone/corticotropin-releasing hormone test DSM Diagnostic and Statistical Manual of Mental Disorders
DST dexamethasone suppression test
ECLIA electrochemiluminescence immunoassay EDTA ethylenediaminetetraacetic acid
ETI Early Trauma Inventory
GLM General Linear Model
GR glucocorticoid receptor
HPA-axis hypothalamic-pituitary-adrenal axis
IQR interquartile range
LUMC Leiden University Medical Center MDD major depressive disorder
M.I.N.I. Mini International Neuropsychiatric Interview
MR mineralocorticoid receptor
NE non-trauma-exposed
PTSD posttraumatic stress disorder
SCID-P Structured Clinical Interview for DSM-III-R Patients
SD standard deviation
SE standard error
SHRP stress hypresponsive period T1 awakening cortisol concentrations
TE trauma-exposed
TSST Trier Social Stress Test
UNIFIL United Nations Interim Force In Lebanon UNPROFOR United Nations Protection Force.
