University of Groningen
Dynamics of the bacterial replisome
Monachino, Enrico
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Publication date: 2018
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Monachino, E. (2018). Dynamics of the bacterial replisome: Biochemical and single-molecule studies of the replicative helicase in Escherichia coli. University of Groningen.
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IOGRAPHY
Enrico Monachino was born in Milan (Italy) on April 26th, 1989. He finished his 1st
level degree in Physics at the University of Trieste in 2011 with a thesis titled “Quantitative experimental determination of carbon dioxide interaction with the (110) surface of a nickel and copper allow” under the supervision of Prof. Giovanni Comelli and Prof. Erik Vesselli. In 2013 he obtained his Master Degree in Condensed Matter Physics with a thesis on “Catalytic reduction of carbon dioxide on a nickel single crystal: an in situ investigation” under the supervision of Prof. Erik Vesselli. Each year in Trieste he obtained a scholarship funded by Collegio per le Scienze “Luciano Fonda”. His work during these years resulted into six papers published in peer-reviewed journals. He then moved to Groningen, the Netherlands, where he started his PhD in November 2013 in the group led by Prof. Antoine M. van Oijen at Zernike Institute for Advanced Materials, University of Groningen. He was hired in the context of the NWO-funded programme “Crowd Management: the physics of genome processing in complex environments”. In March 2015 he moved to Wollongong, NSW, Australia, following Prof. van Oijen and helping him starting his new group in the School of Chemistry, University of Wollongong. A joint PhD degree was started between the University of Groningen and the University of Wollongong. He won the “Best Research Presentation Awards for a Highly Commended talk by a Second Year PhD Student” at the UOW School of Chemistry’s 2015 annual conference and won a poster award at the East Coast Protein Meeting 2017. In 2016, he was invited to present his research to Their Majesties the King and the Queen of the Netherlands, and to the Dutch Minister for the Foreign Affairs, as part of the official launch of the New Holland Scholarship Australia at the University of Sydney, NSW, Australia. His PhD project addressed the dynamics at the E. coli replication fork. In particular, he looked at how the replicative helicase and the polymerase holoenzyme interact with each other and how this affects the molecular mechanism of the replisome. So far his work in the van Oijen lab has resulted into five papers published in peer-reviewed journals.
