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Stepping into the RING: preclinical models in the fight against hereditary breast
cancer
Drost, R.M.
Publication date
2012
Link to publication
Citation for published version (APA):
Drost, R. M. (2012). Stepping into the RING: preclinical models in the fight against hereditary
breast cancer. Het Nederlands Kanker Instituut - Antoni van Leeuwenhoek Ziekenhuis.
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Curriculum vitae & publications
201
A
Publications
Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.
Evers B, Drost R, Schut E, de Bruin M, van der Burg E, Derksen PW, Holstege H, Liu X, van Drunen E, Beverloo HB, Smith GC, Martin NM, Lau A, O'Connor MJ, Jonkers J.
Clin Cancer Res. 2008 Jun 15;14(12):3916-25.
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.
Puppe J, Drost R, Liu X, Joosse SA, Evers B, Cornelissen-Steijger P, Nederlof P, Yu Q, Jonkers J, van Lohuizen M, Pietersen AM.
Breast Cancer Res. 2009;11(4):R63.
Preclinical mouse models for BRCA1-associated breast cancer.
Drost RM, Jonkers J.
Br J Cancer. 2009 Nov 17;101(10):1651-7.
Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.
Bouwman P, Drost R, Klijn C, Pieterse M, van der Gulden H, Song JY, Szuhai K, Jonkers J.
J Pathol. 2011 May;224(1):10-21.
BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.
Drost R, Bouwman P, Rottenberg S, Boon U, Schut E, Klarenbeek S, Klijn C, van der Heijden I, van der Gulden H, Wientjens E, Pieterse M, Catteau A, Green P, Solomon E, Morris JR, Jonkers J.
Cancer Cell. 2011 Dec 13;20(6):797-809.
Each of the four intracellular cysteines of CD36 is essential for insulin- or AMP-activated protein kinase-induced CD36 translocation.
van Oort MM, Drost R, Janssen L, Kerver J, van Doorn J, van der Horst DJ, Luiken JJ, Rodenburg KW.
Manuscript submitted
BRCA1185delAG tumors may acquire therapy resistance through expression of a
RING-less BRCA1 protein via internal translation reinitiation
Drost R, Boon U, Schut E, Wientjens E, Pieterse M, Chondronasiou D, Klijn C, Klarenbeek S, van der Gulden H, van der Heijden I, Rottenberg S, Bouwman P, Jonkers J.
