University of Groningen
From biofilm disinfection to bacterial stem cell modulation and dentin matrix-driven stem cell
mineralization
Petridis, Xenos
DOI:
10.33612/diss.118497988
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Publication date:
2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Petridis, X. (2020). From biofilm disinfection to bacterial stem cell modulation and dentin matrix-driven stem
cell mineralization. University of Groningen. https://doi.org/10.33612/diss.118497988
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Stellingen behorende bij het proefschrift:
A struggle towards optimization of mineralized
tissue engineering
1. Microbial modulation of stem cells from the apical papilla is a risk factor of a successful regenerative endodontic procedure (this thesis).
2. Plasticity of stem cells from the apical papilla is governed by their immunocompetence (this thesis).
3. Topical immunosuppressive treatment can allow for unimpeded odontoblastic differentiation of stem cells from the apical papilla (this thesis).
4. The study biofilm structure opens new opportunities for improved anti-biofilm treatment strategies (this thesis).
5. The use of chlorhexidine for biofilm disinfection must be reconsidered.
6. Mineralized tissue engineering can benefit from the use of umbilical cord-derived stromal cells combined with dentin matrix proteins.
7. “I haven’t failed. I’ve just found 10,000 ways that won’t work” (Thomas Edison). 8. PhD is a marathon and not a sprint race.
9. “Look and you will find it - what is unsought will go undetected” (Sophocles). 10. Success is not a one-man show.
11. When a journey ends, don’t get sad. Take a moment to see what you’ve done, take another one to reset your mind, take a big breath and dive right in again.
