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Intensive care unit benchmarking
Prognostic models for length of stay and presentation of quality indicator values
Verburg, I.W.M.
Publication date
2018
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Citation for published version (APA):
Verburg, I. W. M. (2018). Intensive care unit benchmarking: Prognostic models for length of
stay and presentation of quality indicator values.
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Ilona W.M. Verburg
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Intensive
care unit benchmarking:
prognostic
models for length of stay
and
Intensive care unit benchmarking:
prognostic models for length of stay
and
presentation of quality indicator values
Intensive care unit benchmarking: prognostic models for length of stay and presentation of quality indicator values
PhD thesis, University of Amsterdam, Amsterdam, the Netherlands ©Ilona Verburg, Amsterdam, 2018
ISBN 978-94-6332-283-6
Design and lay out: Ilona Verburg Design cover: Vincent Bakkenist
Printed by: GVO drukkers & vormgevers B.V.
Copyright by Ilona Verburg, Amsterdam, The Netherlands. All rights reserved. No part of this thesis may be reproduced, stored or transmitted in any form or by any means without prior written permission of the author.
A digital version of this thesis can be found at http://dare.uva.nl. This thesis was printed with financial support of:
Stichting Nationale Intensive Care Evaluatie (NICE) and the Department of Medical Informatics AMC.
Intensive care unit benchmarking:
prognostic models for length of stay
and
presentation of quality indicator values
ACADEMISCH PROEFSCHRIFT
ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam
op gezag van de Rector Magnificus prof. dr. ir. K.I.J. Maex
ten overstaan van een door het College voor Promoties ingestelde commissie, in het openbaar te verdedigen in de Agnietenkapel
op vrijdag 2 februari 2018, te 10.00 uur
door Ilona Willempje Maria Verburg geboren te Schoonhoven
Promotiecommissie
Promotores: Prof. dr. N.F. de Keizer AMC-Universiteit van Amsterdam Prof. dr. E. de Jonge Universiteit Leiden
Co-promotores: Dr. R. Holman AMC-Universiteit van Amsterdam Prof. dr. N.B. Peek University of Manchester
Overige leden: Prof. dr. M.B. Vroom AMC-Universiteit van Amsterdam Prof. dr. A.H. Zwinderman AMC-Universiteit van Amsterdam Prof. dr. E.W. Steyerberg Universiteit Leiden
Dr. M.G.W. Dijkgraaf AMC-Universiteit van Amsterdam Dr. L.M. Peelen Universiteit Utrecht
Table of contents
1 General Introduction 1
I Prognostic models for intensive care unit length of stay
2 Which models can I use to predict adult ICU length of stay?
A systematic review 15
3 Comparison of regression methods for modeling intensive care length of
stay 43
4 Is patient length of stay associated with intensive care unit characteristics? 71
II Presentation of quality indicator values
5 The association between outcome-based quality indicators for intensive
care units 99
6 Individual and clustered rankability of ICUs according to case-mix
adjusted mortality 123
7 Guidelines on constructing funnel plots for quality indicators: a case
study on mortality in intensive care unit patients 143
8 General Discussion 171
Appendix
Summary 181
Samenvatting 187
Overview of cited literature 193
Dankwoord 207
Curriculum vitae and portfolio 209