Towards virological monitoring of HIV-1 drug resistance in resource-limited settings - Abbreviations

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Towards virological monitoring of HIV-1 drug resistance in resource-limited

settings

Aitken, S.C.

Publication date

2014

Link to publication

Citation for published version (APA):

Aitken, S. C. (2014). Towards virological monitoring of HIV-1 drug resistance in

resource-limited settings.

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Abbreviations

3TC lamivudine

aa amino acid

AAC accelerated access initiate ABC abacavir

AIDS acquired immunodeficiency syndrome

AIGHD Amsterdam institute for global health and development AMC academic medical centre (Amsterdam)

(c)ART (combination) antiretroviral therapy ARTA affordable resistance test for Africa ARV antiretroviral (drug)

ATV atazanavir AZT zidovudine

cDNA complementary DNA

CCR5 chemokine (C-C motif) receptor 5 CBV combivir

CI confidence interval

CRF circulating recombinant form Ct cycles to threshold

CXCR4 chemokine (C-X-C motif) receptor 4 CV (%) coefficent of variance

d4T stavudine DBS dried blood spot

ddI didanosine dideoxyinosine DLV delavirdine

DNA deoxyribonucleic acid DRM drug resistance mutation DRV darunavir

EDTA ethylenediaminetetraacetic acid EFV efavirenz

EMC encephalomyocarditis virus ENF enfuvirtide

ETR etravarine

EWI early warning indicator

FDA United States food and drug administration FPV fosamprenavir calcium

FTC emtrictabine GP glycoprotein

GRADE (HIV-1) Genotypic Resistance-Algorithm Deutschland GSS genotyping sensitivity score

Abbreviations

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HAART highly active antiretroviral therapy HIV human immunodeficiency virus HIVDB HIV database (Stanford DB) HIVDR HIV drug resistance

HIVResNet global HIV drug resistance network IAS international AIDS society

IC internal control IDV indinavir

IQR inter-quartile range

JCRC joint clinical research centre LED light-emitting diode

LIC low income country LOD level of detection LPV lopinavir

LTR long terminal repeat

MEGA molecular evolutionary genetics analysis MVC maraviroc

mRNA messenger RNA n number (of samples)

NACCAP Netherlands African partnership for capacity development and clinical interventions against poverty-related diseases

NCBI national centre for biotechnology information NA nucleic acid

NFV nelfinavir

NGO non-governmental organization NGS next generation sequencing NMC Ndlovu medical centre

NNRTI non-nucleoside reverse transcriptase inhibitor NPV negative predictive value

NRTI nucleoside reverse transcriptase inhibitor NVP nevirapine

NWO/WOTRO Netherlands organisation for scientifid reaseach for global development

PASER PharmAccess African studies to evaluate resistance PBMC peripheral blood mononuclear cells

PCR polymerase chain reaction (b)PI (boosted) protease inhibitor POC point-of-care

PMTCT prevention of mother-to-child transmission of HIV PPV positive predictive value

8

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PR protease

RAL raltegravir

RDI HIV resistance response database initiative RPV rilpivirine

RLS resource-limited settings RNA ribonucleic acid

RRS resource-rich settings

RT(I) reverse transcriptase (inhibitor)

RT-PCR reverse transcriptiase polymerase chain reaction RTV ritonavir

SANBI South African national bioinformatics institute SATuRN Southern African treatent resistance network SD standard deviation

SQV saquinavir mesylate

TAM thymidine analogue mutation TDF tenofovir

TDR transmitted drug resistance TPV tipranavir

UMCU university medical centre Utrecht UNICEF United Nations children’s fund

UNAIDS joint United Nations programme on HIV/AIDS USD United States dollar

VF(A) virological failure (assay) VL (HIV) viral load

WB whole blood