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Host genetic effects on HIV-1 replication in macrophages
Bol, S.M.
Publication date
2011
Link to publication
Citation for published version (APA):
Bol, S. M. (2011). Host genetic effects on HIV-1 replication in macrophages.
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Curriculum Vitae
Sebastiaan Bol was born in Enschede (Twente), The Netherlands on March 15, 1978. His long and winding road to success started with his lower general secondary education at the Juliana van Stolberg MAVO in Enschede. After graduating, he continued his studies at the upper secondary vocational education in business and administration (MEAO) at the Oosterborgh College in Enschede. As a result of his eagerness to learn and his persever-ance, he was able to complete the subjects of biology and chemistry at the higher general secondary education (HAVO) level by self-tuition, which allowed him to study Clinical Nutrition at the Hogeschool van Amsterdam, University of Applied Sciences, from 1999 to 2003. As part of this study, he performed a 4-month internship at the Department of Clinical Nutrition of the University of Kuopio, Finland where he studied the relationship between uncoupling protein-1 polymorphisms and the diseases obesity and type-2 diabetes. During this period, he particularly enjoyed the tranquility and the space of the Finnish landscape, which fuelled his love for nature untouched. He then wrote his bachelor’s thesis at the Department of Dietetics of the Leiden University Medical Center on the subject of feeding strategy and nutritional requirements for infants and children with chylothorax, for which he was awarded the prestigious Novartis dietetics price. In June 2003, he received his Bachelor’s degree cum laude. Subsequently, he started the study Medical Biotechnology at Wageningen University. He performed internships at the Laboratory of Molecular Biology of Wageningen University on methyltransferases in Arabidopsis thaliana roots and at the Laboratory of Genetic Metabolic Diseases of the Academic Medical Center in Amsterdam on identification of the function of the human enzyme tafazzin. He received his Master’s degree cum laude in January 2007.
Driven by his fascination for science and his ambition to reach ever higher, he decided to perform a challenging PhD-project at the crossroads of genetics and virology at the Depart-ment of Clinical Viro-Immunology at Sanquin Research (University of Amsterdam) under direct supervision of dr. Angélique van ’t Wout, starting in February 2007. This department joined the Department of Experimental Immunology at the Academic Medical Center of the University of Amsterdam in December 2007. The first year of his work was characterized by the laborious collection of samples and data from over 500 blood donors, which formed the basis of his subsequent genetic studies. In the following three years, he continued to implement this novel research line and worked hard to generate the results that are described in this thesis. Being eager for success, progress was painfully slow at times. However, helped by his good eye for detail and his pursuit to comprehensiveness, he managed to produce five first-author manuscripts, of which to date three have been published in peer-reviewed journals.
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Sebastiaan is a perfectionist and an idealist, who strives to make this world a better place. He has been a vegetarian since he was 14 years old, and is actively involved in a small-scale project for children in a township near Cape Town, South Africa. His passions include music, movies and sports, in particular running, but also snooker, soccer, cycling, ice-hockey, basketball and baseball.
At the department where he performed his PhD research, he met the love of his life, Evelien Bunnik, and he will marry her four days after the defense of this thesis. Later in July, they will pack their bags and move to Riverside, California, where he will continue his career as a post-doc in the field of Genetics and Genomics. To stay updated on the major and minor events in his life and career, follow Sebastiaan on Twitter at www.twitter.com/seb_bol. April 2011
