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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

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Cardiovascular risk in women with uterine fibroids of different ethnic groups

Haan, Y.C.L.

Publication date

2020

Document Version

Other version

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Citation for published version (APA):

Haan, Y. C. L. (2020). Cardiovascular risk in women with uterine fibroids of different ethnic

groups.

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Cardiovascular risk in women with uterine

fibroids of different ethnic groups

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Copyright © Yentl C.L. Haan, 2020

No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, without prior written permission of the author.

ISBN: ISBN 978-94-6375-754-6 Author Yentl Haan

Cover design Caroline Bruikman

Lay-out: Ridderprint | www.ridderprint.nl Printed by: Ridderprint | www.ridderprint.nl

The printing of this thesis was financially supported by:

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Cardiovascular risk in women with uterine

fibroids of different ethnic groups

ACADEMISCH PROEFSCHRIFT

ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam op gezag van de Rector Magnificus

prof. dr. ir. K.I.J. Maex

ten overstaan van een door het College voor Promoties ingestelde commissie, in het openbaar te verdedigen in de Agnietenkapel

op donderdag 13 februari 2020, te 12.00 uur

door Yentl Christina Louise Haan geboren te Bussum

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PROMOTIECOMMISSIE

Promotor: prof. dr. S. Middeldorp AMC-UvA

Copromotor: dr. L.M. Brewster Stichting Creatine Kinase Overige leden: prof. dr. C. Schultsz AMC-UvA

prof. dr. R.J.G. Peters AMC-UvA dr. N.R. Bindraban AMC-UvA prof. dr. E.T. van Bavel AMC-UvA

prof. dr. J.C. Seidell Vrije Universiteit Amsterdam Faculteit der Geneeskunde

Financial support by the Dutch Heart Foundation for the publication of this thesis is gratefully acknowledged

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TABLE OF CONTENTS

Chapter 1 Introduction and outline of the thesis 9

Chapter 2 Hypertension risk in Dutch women with symptomatic

uterine fibroids 21

Chapter 3 The Risk of Hypertension and Cardiovascular

Disease in Women with Uterine Fibroids 37

Chapter 4 Cardiovascular disease in women with uterine

fibroids: data from NHANES 61

Chapter 5 Increased arterial stiffness in women with uterine fibroids 79

Chapter 6 Creatine kinase as a marker of obesity in a multi-ethnic

population 97

Chapter 7 Summary and Perspectives 117

Appendices

Nederlandse samenvatting 131

List of publications 139

Authors and affiliations 141

Portfolio 143

Dankwoord 145

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