Mechanistic studies on transcutaneous vaccine delivery : microneedles, nanoparticles and adjuvants Bal, S.M.

In this study we co-encapsulated ovalbumin (OVA) and a Toll-like receptor (TLR) ligand (PAM 3 CSK 4 (PAM) or CpG) in cationic liposomes and investigated the effect of

Indeed after intranodal injection a rapid uptake of fluorescently labelled OVA and CpG by DCs was observed as can be inferred from the high percentage of OVA + and CpG +

Independent of the microneedle array used and the sequence of microneedle treatment and vaccine application, transcutaneous immunisation with the physical mixture

During her study she did two internships with the titles “Needle-array enhanced iontophoretic delivery of cascade blue labeled dextrans” and “Dendritic cell activation and cytokine

In zowel de studies met OVA als die met DT verhoogden de TMC nanodeeltjes en de mengsels de antistoftiters in vergelijking met antigeen zonder adjuvans.. Het antistoffenprofiel

Bal SM*, Slütter B*, Verheul RJ, Bouwstra JA, Jiskoot W: Adjuvanted, antigen loaded N- trimethyl chitosan nanoparticles for nasal and intradermal vaccination: adjuvant-

Helaas (voor ons) vertrok je naar Japan, wat een groot gemis voor de vakgroep was. Nadat Elly vertrok, heeft Myrra veel van de cellab taken overgenomen.. The vaccine team

Although nanoparticles are suitable to ensure concomitant delivery of antigen and adjuvant to dendritic cells, smaller antigen-adjuvant conjugates are more suitable