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University of Groningen

Towards sustainable management of arboviral diseases Elsinga, Jelte

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2018

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Elsinga, J. (2018). Towards sustainable management of arboviral diseases: A multidisciplinary mixed-methods approach in Curaçao and Venezuela. University of Groningen.

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TOWARDS SUSTAINABLE

MANAGEMENT OF

ARBOVIRAL DISEASES

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Towards sustainable management of

arboviral diseases

A multidisciplinary mixed-methods approach in Curaçao and Venezuela

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the Rector Magnificus Prof. E. Sterken

and in accordance with the decision by the College of Deans. This thesis will be defended in public on

Wednesday 2 May 2018 at 16.15 uur

by

Jelte Elsinga

born on 27 December 1990 in Ermelo

The author gratefully acknowledges the financial support for printing this thesis by:

This thesis was printed by NetzoDruk® ISBN

978-94-034-0627-5 (Hardcopy) 978-94-034-0626-5 (Digital) Cover design Liselot Visser Cover illustration Maarten Krukkert Design Leanne de Munnik Copyright © Jelte Elsinga, 2018

All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means without the permission of the author and, when appropriate, the publisher holding the copyrights of the published studies.

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Towards sustainable management of

arboviral diseases

A multidisciplinary mixed-methods approach in Curaçao and Venezuela

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the Rector Magnificus Prof. E. Sterken

and in accordance with the decision by the College of Deans. This thesis will be defended in public on

Wednesday 2 May 2018 at 16.15 uur

by

Jelte Elsinga

born on 27 December 1990 in Ermelo

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Supervisors

Prof. A.W. Friedrich Prof. M.P. Grobusch

Co-supervisors

Dr. A. Bailey Dr. A. Tami

Assessment Committee

Prof. S.A. Reijneveld Prof. U. Gross Prof. H.H. Haisma

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Table of Contents

Chapter 1. Introduction. Towards sustainable management of arboviral diseases 6

Chapter 2. Health seeking behaviour and treatment intentions of

dengue and fever: a household survey of children and adults in Venezuela 20

PLoS Neglected Tropical Diseases 2015; 9(12):e0004237

Chapter 3. Accessing Healthcare in Venezuela: a Community based

Study on Health Centre Preferences in the Case of Dengue and Fever 46

Manuscript submitted

Chapter 4. Knowledge, Attitudes and Preventive Practices regarding

Dengue in Maracay, Venezuela 70

The American Journal of Tropical Medicine and Hygiene; accepted for

publication (modified version)

Chapter 5. Community participation in mosquito breeding site control:

an interdisciplinary mixed methods study in Curaçao 90

Parasites & Vectors 2017; 10:434

Chapter 6. Long-term chikungunya sequelae in Curaçao: burden,

determinants and a novel classification tool 128

Journal of Infectious Diseases 2017; 216(5):573–81

Chapter 7. Health-Related Impact on Quality of Life and Coping

Strategies for Chikungunya: A Qualitative Study in Curaçao 156

PLoS Neglected Tropical Diseases 2017; 11(10):e0005987

Chapter 8. Consequences of a recent past dengue infection for acute and

long-term chikungunya outcome: a retrospective cohort study in Curaçao 184

Tracel Medicine and Infectious Disease; in press accepted manuscript

(modified version)

Chapter 9. Summary and future perspectives 206

Survey instruments and interview guides 214

Nederlandse samenvatting 228

Word of thanks 238

About the author 242

Supervisors

Prof. A.W. Friedrich Prof. M.P. Grobusch

Co-supervisors

Dr. A. Bailey Dr. A. Tami

Assessment Committee

Prof. S.A. Reijneveld Prof. U. Gross Prof. H.H. Haisma

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