University of Groningen
Endothelial plasticity in fibrosis and epigenetics as a therapeutic target
Hulshoff, Melanie
DOI:
10.33612/diss.146265795
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Publication date: 2020
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
Hulshoff, M. (2020). Endothelial plasticity in fibrosis and epigenetics as a therapeutic target. University of Groningen. https://doi.org/10.33612/diss.146265795
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Propositions accompanying the PhD thesis
Endothelial plasticity in fibrosis and epigenetics as a therapeutic target
By
Melanie S. Hulshoff
1) Endothelial plasticity is regulated by epigenetic modifications (this thesis).
2) Standardization of in vitro models of EndMT is essential to identify the underlying epigenetic mechanisms of EndMT (this thesis).
3) Unraveling the underlying epigenetic mechanisms of EndMT depends on the development of in vivo models of EndMT (this thesis).
4) A cure for fibrosis depends on epigenetic targeting (this thesis). 5) Fibroblasts are not derived from EndMT (Moore-Morris et al).
6) Vaccines tailored to the coronavirus (SARS-CoV-2) do not offer protection against novel coronaviruses (Giurgea et al).
7) Epigenetic alterations play an underestimated role in the onset of coronavirus disease complications (Khan et al).
8) Education is the difference between wishing you could help others and being able to help them (Russel M. Nelson).
