Application of poly(trimethylene carbonate) and calcium phosphate composite biomaterials in
oral and maxillofacial surgery
Zeng, Ni
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Publication date: 2017
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Zeng, N. (2017). Application of poly(trimethylene carbonate) and calcium phosphate composite biomaterials in oral and maxillofacial surgery. Rijksuniversiteit Groningen.
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A P P L I C AT I O N O F P O LY ( T R I M E T HYL E N E C A R B O N AT E )
A N D C A LC I U M P H O S P H AT E CO M P O S I T E B I O M AT E R I A L S
I N O R A L A N D M AX I L LO FAC I A L S U R G E RY
Ni Zeng
ISBN (printed version) 978-90-367-9408-4 ISBN (electronic version) 978-90-367-9407-7
Cover design, layout and printing: Off Page, Amsterdam
Universitair Medisch Centrum Groningen, Rijksuniversiteit Groningen, Groningen, Nederland Copyright © 2016 by Ni Zeng
A P P L I C AT I O N O F P O LY ( T R I M E T HYL E N E C A R B O N AT E )
A N D C A LC I U M P H O S P H AT E CO M P O S I T E B I O M AT E R I A L S
I N O R A L A N D M AX I L LO FAC I A L S U R G E RY
PhD thesis
to obtain the degree of PhD at the University of Groningen
on the authority of
the Rector Magnificus Prof. E. Sterken and in accordance with the decision by the College of Deans. This thesis will be defended in public on Monday 16 January 2017 at 12.45 hours
by Ni Zeng born on 21 April 1986
CO - S U P E R V I S O R
Dr. R. KuijerA S S E S S M E N T CO M M I T T E E
Prof. R.A. BankProf. G.J. Meijer Prof. E.A.J.M. Schulten
PA R A N I M F E N
Simon Robert Hemelaar Arden Leander van ArnhemTA B L E O F CO N T E N TS
Chapter 1 General introduction and aim of the thesis 7 Chapter 2 Barrier Membranes for Guided Bone Regeneration in Implant Surgery: 17
a review
Chapter 3 Histological Evaluation of Degradable Guided Bone Regeneration 39 Membranes Prepared from Poly(trimethylene carbonate)
and Biphasic calcium phosphate composites
Chapter 4 Evaluation of Novel Resorbable Membranes for Bone Augmentation 51 in A Rat Model
Chapter 5 Poly(trimethylene carbonate)-based Composite Materials 65 for Reconstruction of Critical-sized Cranial Bone Defects in Sheep
Chapter 6 Evaluation of Osteoinductivity of Different Calcium Phosphate 87 and PTMC-Calcium Phosphate Composite Biomaterials in a Sheep Model
Chapter 7 General Discussion 109
Appendix Summary 119
Samenvatting 122
摘要 125