University of Groningen
Shigella spp. and entero-invasive Escherichia coli
van den Beld, Maaike
DOI:
10.33612/diss.101452646
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Publication date: 2019
Link to publication in University of Groningen/UMCG research database
Citation for published version (APA):
van den Beld, M. (2019). Shigella spp. and entero-invasive Escherichia coli: diagnostics, clinical
implications and impact on public health. University of Groningen. https://doi.org/10.33612/diss.101452646
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Stellingen behorende bij het proefschrift
Shigella spp.
and entero-invasive Escherichia coli
Diagnostics, clinical implications and impact on public health
1. All Shigella spp. are highly related to each other and to Escherichia coli, and should taxonomically be classified as such – this thesis
2. MALDI-TOF mass spectrometry should not be used for differentiation of Shigella spp. and E. coli – this thesis
3. It will probably never be feasible to develop a simple, non-laborious diagnostic test that is able to differentiate between Shigella spp. and EIEC – this thesis
4. There are no differences in patient outcome that justify the current control guidelines and case definition of shigellosis in which infections with EIEC or infections with
Shigella and EIEC that are only molecularly detected are not incorporated – this thesis
5. Differences in patient outcomes in shigellosis are not caused by the identity or specific features of isolates – this thesis
6. Laboratory surveillance based on whole genome sequencing of Shigella spp. is of added value for current epidemiological surveillance and is essential to comprehend domestic transmissions and linking them to international clusters – this thesis 7. Shigella spp. are perfectly human-adapted pathogens and a formidable foe – this
thesis, Kotloff et al. 2017, Lancet Glob Health, and Lampel et al. 2018, EcoSal Plus
8. Follow the mentor’s spirit, not the mentor’s footsteps – Dr. Kiyoshi Shiga
9. The three great essentials to achieve anything worthwhile are, first, hard work; second, stick-to-it-iveness; third, common sense – Thomas A. Edison
10. A party without cake is really just a meeting – Julia Child 11. Ja-maar wat als alles lukt? – Berthold Gunster, Omdenken
Maaike van den Beld 11 September 2019
