Novel insights in reperfusion therapy and stent thrombosis in the drug eluting stent era
Hassan, A.K.M.
Citation
Hassan, A. K. M. (2009, January 14). Novel insights in reperfusion therapy and stent
thrombosis in the drug eluting stent era. Retrieved from https://hdl.handle.net/1887/13406
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/13406
Note: To cite this publication please use the final published version (if applicable).
Novel insights in
reperfusion therapy and stent thrombosis in the drug eluting stent era
Ayman Khairy Mohamed Hassan
The studies described in this thesis were performed at the department of Cardiology of the Leiden University Medical Center, the Netherlands.
Copyright ©Ayman Khairy Mohamed Hassan, Leiden, the Netherlands. All rights reserved.
No part of this book may be reproduced or transmitted in any form or by any means, without prior written permission of the author.
Lay out: Legatron Electronic Publishing
Printed by: PrintPartners Ipskamp, Enschede (www.ppi.nl) ISBN: 978-90-9023809-8
Financial support to the costs associated with the publication of this thesis from Cardiology department, Leiden University Medical Center, Leiden, the Netherlands.
Novel insights in reperfusion therapy and stent thrombosis in the drug eluting stent era
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op woensdag 14 januari 2009
klokke 15:00 uur
door
Ayman Khairy Mohamed Hassan
Geboren te Assiut, Egypt 1975
Promotiecommissie
Promoters: Prof. dr. J.W.Jukema Prof. dr. M.J.Schalij
Referent: Prof. dr. A.H. Zwinderman
(Academic Medical centre, University of Amsterdam, Amsterdam)
Overige leden: Prof. dr. A. van der Laarse Prof. dr. E.E. van der Wall Dr. D.E. Atsma
Prof. dr. R. Klautz
To the soul of my precious mother To my great father and my dear
sister
To my little family……….., My lovely wife mona
my son mostafa
and my daughter salwa
TABLE OF CONTENTS
Chapter 1 General introduction and outline of the thesis 9
Chapter 2 In-ambulance abciximab administration in STEMI patients prior to 27 primary PCI is associated with smaller infarct size, improved LV function and lower incidence of heart failure: Results from the Leiden MISSION!
acute myocardial infarction treatment optimization program
Chapter 3 Incidence, patient’s characteristics and predictors of aborted myocardial 43 infarction in patients undergoing primary PCI: prospective study
comparing pre- and in-hospital abciximab pretreatment
Chapter 4 Aborted myocardial infarction in patients undergoing primary PCI: 59 long term outcomes
Chapter 5 Usefulness of Peak Troponin-T to Predict Infarct Size and Long-Term 71 Outcome in Patients with First Acute Myocardial Infarction after Primary Percutaneous Coronary Intervention
Chapter 6 The risk of late acquired stent malapposition is higher after drug-eluting 87 stent compared to bare-metal stent implantation and is associated with late stent thrombosis: Meta-analysis and systematic review
Chapter 7 Summary, conclusions and Future perspectives 103
Chapter 8 Samenvatting en conclusie 109
Acknowledgments 115
Curriculum vitae 117