Arousal, exploration and the locus coeruleus-norepinephrine system
Jepma, M.
Citation
Jepma, M. (2011, May 12). Arousal, exploration and the locus coeruleus-norepinephrine system. Retrieved from https://hdl.handle.net/1887/17635
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Arousal, exploration and the
locus coeruleus-norepinephrine system
Marieke Jepma
ISBN 978-94-91211-30-0
Copyright © Marieke Jepma, 2011
Cover design: Hanneke and Marieke Jepma Printed by Ipskamp Drukkers B.V. Amsterdam
The research presented in this thesis was supported by a VIDI grant from the Netherlands Organization for Scientific Research (NWO) to Sander Nieuwenhuis.
Printing of this thesis was supported by
BioSemi
.Arousal, exploration and the
locus coeruleus-norepinephrine system
Proefschrift ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van de Rector Magnificus Prof. mr. P. F. van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op donderdag 12 mei 2011 klokke 11:15 uur
Door
Marieke Jepma
geboren te Utrecht in 1983
Promotiecommissie
Promotor Prof. Dr. B. Hommel Co-promotor Dr. S. Nieuwenhuis
Overige leden Dr. G. P. H. Band
Dr. R. Cools, Radboud Universiteit Nijmegen Prof. Dr. R. de Jong, Rijksuniversiteit Groningen Prof. Dr. L. J. Kenemans, Universiteit Utrecht
Prof. Dr. K. R. Ridderinkhof, Universiteit van Amsterdam Prof. Dr. S. A. R. B. Rombouts
Contents
Chapter 1: General introduction 7
Chapter 2: Pupil diameter predicts changes in the exploration-exploitation 17 trade-off: Evidence for the adaptive gain theory
Chapter 3: The role of the noradrenergic system in the exploration- 37 exploitation trade-off: A psychopharmacological study
Chapter 4: Neurocognitive function in dopamine-β-hydroxylase deficiency 63 Chapter 5: Neural mechanisms underlying the induction and relief of 97
perceptual curiosity
Chapter 6: The effects of accessory stimuli on information processing: 113 Evidence from electrophysiology and a diffusion-model analysis
Chapter 7: Temporal expectation and information processing: 141 A model-based analysis
Chapter 8: Summary 167
References 170
Nederlandse samenvatting 191
Dankwoord 199
Curriculum Vitae 200
