Modulation of the canonical Wnt signaling pathway in bone and cartilage Miclea, R.L.

Since in our experimental set-ups described in chapter 6 the GIN-induced effects reflect some of the pathological find- ings normally seen in

Glycogen synthase kinase 3 controls endo- chondral bone development: contribution of fibroblast growth factor 18.. Cre recombinase: the universal reagent for genome

171 Tijdens de skeletontwikkeling zijn de eiwitniveaus van β-catenine in de canonische Wnt signaleringsroute doorslaggevend voor de differentiatie van skeletvoorlopercellen (SVC)

During his medical study he performed a 3-months research project at the subdivision of Pediatric Endocrinol- ogy of the Leiden University Medical Center (LUMC) under

Deletions of Wnt or β-catenin result in absent osteogenesis and increased osteoclastogenesis, whereas expression of a stable form of β-catenin in the skeleton results in

Peripheral blood cells were stained with HLA-A2.1 tetramers containing the tyrosinase368–376 peptide followed by staining with a panel of lineage antibodies, as described in

Blades and blade fragments seem to have been especially used for longitudinal motions, mainly on plant material (7/12). Flake and flake fragments are used in different motions on

This shape also occurs in the combination artefacts (see below). The shape is the result of intensive use in a repetitive abrasive motion, carried out from different angles. In