Stem cell therapy for cardiovascular disease : answering basic questions regarding cell behavior
Bogt, K.E.A. van der
Citation
Bogt, K. E. A. van der. (2010, December 16). Stem cell therapy for
cardiovascular disease : answering basic questions regarding cell behavior.
Retrieved from https://hdl.handle.net/1887/16249
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
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Stem Cell Therapy for Cardiovascular Disease
Answering basic questions regarding cell behavior
PROEFSCHRIFT
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van de Rector Magnificus Prof. mr. P.F. van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op donderdag 16 december 2010 klokke 15.00 uur door
Koen Elzert Adriaan van der Bogt
geboren te Nieuwveen in 1981
PROMOTIECOMMISSIE
Promotores: Prof. Dr. J.F. Hamming
Prof. Dr. R.C. Robbins (Stanford University, USA) Co-promotor: Dr. J.C. Wu (Stanford University, USA)
Overige leden: Prof. Dr. C.L. Mummery Prof. Dr. P.H. Quax
The research as described in this thesis has been a collaborative effort of the Department of Cardiothoracic Surgery and the Molecular Imaging Program at Stanford University (California, USA), and the Department of Surgery, Leiden University Medical Center (The Netherlands).
The printing of this thesis was financially supported by the Netherlands Heart Foundation and the J.E. Jurriaanse Foundation. The research was supported by grants from the Fulbright Foun- dation, the VSB fund, the Prof. Michaël-van Vloten Foundation, the American Heart Associa- tion, the Collegium Chirurgicum Neerlandicum, ADinstruments, Millar Instruments, Synthes, Triplinq Hosted Solutions, ChipSoft and Servier Nederland Farma B.V.
To my family
TABLE OF CONTENTS:
Chapter 1: General Introduction 7
PART I: EMBRYONIC STEM CELLS
Chapter 2: Multimodal evaluation of in vivo magnetic resonance imaging of 19 myocardial restoration by mouse embryonic stem cells.
J Thorac Cardiovasc Surg. 2008 Oct;136(4):1028-1037.e1.
Chapter 3: Spatial and temporal kinetics of teratoma formation from murine 37 embryonic stem cell transplantation.
Stem Cells Dev. 2007 Dec;16(6):883-91.
Chapter 4: Molecular imaging of human embryonic stem cells: keeping an eye 53 on differentiation, tumorigenicity and immunogenicity.
Cell Cycle. 2006 Dec;5(23):2748-52.
Chapter 5: Clinical hurdles for the transplantation of cardiomyocytes derived 67 from human embryonic stem cells: role of molecular imaging.
Curr Opin Biotechnol. 2007 Feb;18(1):38-45.
PART II: ADULT STEM CELLS
Chapter 6: Comparison of different adult stem cell types for treatment of 85 myocardial ischemia.
Circulation. 2008 Sep 30;118(14 Suppl):S121-9.
Chapter 7: Comparison of transplantation of adipose tissue- and bone 107 marrow-derived mesenchymal stem cells in the infarcted heart.
Transplantation. 2009 Mar 15;87(5):642-52.
Chapter 8: Micro Computed Tomography for Characterization of 131 Murine Cardiovascular Disease Models.
JACC Cardiovasc Imaging. 2010 Jul;3(7):783-5.
Chapter 9: Molecular Imaging of Bone Marrow Mononuclear Cell Survival 141 and Homing in a Model of Murine Peripheral Artery Disease.
Submitted
Chapter 10: Summary and Discussion 161
Chapter 11: Summary in Dutch 173
Chapter 12: List of Publications 180
Curriculum Vitae 182
Acknowledgements 184
