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Het is van groot belang dat professionals, die werkzaam zijn in het JGZ veld,  promotieonderzoek doen1. Het vergroot de kwaliteit en wetenschappelijke  onderbouwing van de

To investigate if local Lenti-Cre delivery could induce ILC formation driven by loss of tumor suppressor genes (TSGs) rather than activation of a potent oncogene such as

(A) Unsupervised clustering (Euclidean distance, average linkage) of the SB-induced tumors with reference mouse models and human breast cancer samples from TCGA, showing

Since the migration speed of the MDA-MB-231 and H1299 cells was only significantly affected by the expression of p53-R248Q and p53-R248Q-TA, these cell lines were selected

We show that α3β1 can regulate pro-tumorigenic signaling pathways and promote formation of pro-tumorigenic tumor environment during the initiation phase of two-stage skin

Title: The diverse roles of integrin α3β1 in cancer: Lessons learned from skin and breast carcinogenesis.. Issue

Next, we investigated the role of HB SC-residing α3β1 in skin carcinogenesis by submitting K19 Itga3 KO and WT mice to the complete DMBA/TPA carcinogenesis.. Integrin