Table 1. Overview of cut-off values for low disease activity and remission for different composite scores.
Composite score Formula Low disease
activity
Remission
DASa 0.54*√RAI + 0.065*SJC + 0.33*ln(ESR) + 0.007*PTGLBL
≤2.4 <1.6
DAS28a 0.56*√TJC28 + 0.28*√SJC28 + 0.70*ln(ESR) + 0.014* PTGLBL
≤3.2 <2.6
DAS28-CRPa 0.56*√TJC28 + 0.28*√SJC28 +
0.36*ln(CRP+1) + 0.014* PTGLBL + 0.96
≤2.9 <2.4
SDAI SJC + TJC + PTGLBL + DRGLBL + CRP ≤11 ≤3.3
CDAI SJC + TJC + PTGLBL + DRGLBL ≤10 ≤2.8
ACR/EULAR Boolean remission
TJC, SJC, CRP mg/dl and PTGLB (0-10 scale)
-- All measures
≤1
Ultrasound remission
Various definitions including no or limited power Doppler activity and limited Grey scale ultrasound, possibly combined with clinical remission.
DAS = disease activity score, ESR = erythrocyte sedimentation rate, CRP = c-reactive protein, RAI = Ritchie Articular Index, TJC = tender joint count, SJC = swollen joint count, PTGLBL = visual
analogue scale patient assessment of global health, DRGLBL = visual analogue scale physician assessment of global health.
aAlternative formulas exist for the DAS(28) based on CRP, based on 3 components (no PTGLBL) or based on 3 components and CRP. These use the cut-offs of the original DAS(28).
