Mannose-binding lectin: The Dr. Jekyll and Mr. Hyde of the innate immune system.

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Mannose-binding lectin: The Dr. Jekyll and Mr. Hyde of the innate

immune system.

Bouwman, L.H.

Citation

Bouwman, L. H. (2006, January 25). Mannose-binding lectin: The Dr. Jekyll and Mr. Hyde

of the innate immune system. Retrieved from https://hdl.handle.net/1887/4277

Version:

Corrected Publisher’s Version

License:

Licence agreement concerning inclusion of doctoral thesis in the

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Acknowledgements 149

A C K N O W LED G EM EN TS

Although this thesis bears yet one name, it was realized with the help of various individuals. B eing aware of the danger that ex ists by listing the names of people who direc tly or indirec tly c ontributed to this thesis, I have no doubt unintentionally overlook ed important c ontributors, therefore I apologize beforehand.

H owever, I would lik e to ex press my apprec iation to all c olleagues of the S urgery, N ephrology, G astroenterology and H epatology and Immunoheamatology and B lood-transfusion departments. F urthermore, I would lik e to thank the personnel of the operation theatre. E spec ially, I would lik e to thank the following people to whom I am indebted for reasons best k nown to themselves: M arja van B rak el, M ohamed D aha, F rederiek e van D uijnhoven, Jac q ues D uijs, G aby D uink erk en, P eter E erligh, R einier van der G eest, P ieter van de L inde, M irre de N oo, K oen P eeters, G abrië lle P ink se, Joost R othbarth, S andro S c haapherder, Arno van der S lik , O dette T ijsma and M artijn van der W erff.

I am grateful for the c ontinuous love and support of my parents and brothers, not only during the period of this P hD -projec t, but also in the last 3 2 years. In mentioning my in-laws I would lik e to ex tend my apprec iation of their support and affec tion.

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Curriculum Vitae 151

CU R R ICU LU M V ITAE

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List of abbreviations 153

LIST OF AB B REVIATIONS

ANOVA analysis of variance

AP alternative pathway

BSA bovine serum albumin

CDR C-terminal carbohydrate-recognition domain

CP classical pathway

CSI clinically signifi cant infections ELISA enzyme linked immunosorbent assay GVB gelatin veronal buffer

I/R ischemia/reperfusion

LP lectin pathway

mAb monoclonal antibody

MAC membrane attack complex

MASP MBL-associated serine protease

MBL mannose-binding lectin

MILR mixed islet/lymphocyte reaction

MLR mixed lymphocyte reaction

MP MBL pathway

OLA oligonucleotide ligation assay OLT orthotopic liver transplantation p60 protein 60 of Listeria monocytogenes PBMC peripheral blood mononuclear cells PBS phosphate buffered saline

PCR polymerase chain reaction R correlation coeffi cient

RF rheumatoid factor

SLE systemic lupus erythematosus

SNP single nucleotide polymorphism