University of Groningen
The right ventricle in heart failure with preserved ejection fraction
Gorter, Thomas Michiel
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Publication date: 2018
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Gorter, T. M. (2018). The right ventricle in heart failure with preserved ejection fraction. Rijksuniversiteit Groningen.
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Financial support by Abbott Medical Nederland BV, Actelion Pharmaceuticals Nederland BV, Bayer BV, Bracco Imaging Europe BV, GUIDE, Medis Medical Imaging Systems BV, Novartis Pharma BV and Rijksuniversiteit Groningen for the publication of this thesis, is gratefully acknowledged.
Copyright 2018 Thomas Michiel Gorter
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ISBN 978-94-6233-971-2
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The Right Ventricle
In Heart Failure with Preserved Ejection Fraction
The right ventricle in heart failure with
preserved ejection fraction
Proefschrift
ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen
op gezag van de
rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties.
De openbare verdediging zal plaatsvinden op woensdag 6 juni 2018 om 14.30 uur
door
Thomas Michiel Gorter
geboren op 25 juli 1988 te Enschede
Promotor
Prof. dr. D.J. van Veldhuisen
Copromotores Dr. J.P. van Melle Dr. M. Rienstra Dr. T.P. Willems Beoordelingscommissie Prof. dr. J.J. Bax
Prof. dr. M.P. van den Berg Prof. dr. R.A.J.O. Dierckx
Paranimfen
Sander Gorter
Chapter 1 Introduction and aims
10
Chapter 2 Right ventricular dysfunction in heart failure with
preserved ejection fraction: a systematic review and meta-analysis
19
Eur J Heart Fail 2016
Chapter 3 Right ventricular-vascular coupling in heart failure
with preserved ejection fraction and pre- versus post-capillary pulmonary hypertension
58
Eur Heart J Cardiovasc Imaging 2018
Chapter 4 Exercise unmasks distinct pathophysiologic
features in heart failure with preserved ejection fraction and pulmonary vascular disease
77
Submitted
Chapter 5 Right heart dysfunction in heart failure with
preserved ejection fraction: The impact of atrial fibrillation
97
J Card Fail 2018
Table of
Contents
Chapter 6 Diabetes mellitus and right ventricular dysfunction
in heart failure with preserved ejection fraction
113
Am J Cardiol 2018
Chapter 7 Right heart dysfunction and failure in heart failure
with preserved ejection fraction: mechanisms and management
127
Eur J Heart Fail 2018
Chapter 8 Measuring pulmonary artery pressures in heart
failure: A new useful diagnostic tool?
171
Circulation 2017
Chapter 9 General discussion and future perspectives
177
Appendices Dutch Summary
193
About the author
199
Acknowledgments