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University of Groningen Bacterially derived carbon quantum dots for biofilm control Wu, Yanyan

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University of Groningen

Bacterially derived carbon quantum dots for biofilm control Wu, Yanyan

DOI:

10.33612/diss.171939593

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2021

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Wu, Y. (2021). Bacterially derived carbon quantum dots for biofilm control. University of Groningen. https://doi.org/10.33612/diss.171939593

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Bacterially derived carbon quantum dots

for biofilm control

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Bacterially derived carbon quantum dots for biofilm control

University Medical Center Groningen, University of Groningen Groningen, The Netherlands

Copyright © 2021 by Yanyan Wu Cover: Yanyan Wu

Layout: Yanyan Wu

Printed by Ipskamp Printing

ISBN (printed version): 978-94-6421-368-3 ISBN (electronic version): 978-94-6421-370-6

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Bacterially derived carbon

quantum dots for biofilm control

PhD thesis

to obtain the degree of PhD at the University of Groningen

on the authority of the

Rector Magnificus Prof. C. Wijmenga and in accordance with

the decision by the College of Deans. This thesis will be defended in public on

Wednesday 7 July 2021 at 9.00 hours by

Yanyan Wu

born on 4 September 1989 in Guangxi, China

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Supervisors

Prof. Y. Ren

Prof. H.J. Busscher

Prof. H.C. van der Mei

Assessment Committee

Prof. H. Koo

Prof. H.W. Frijlink

Prof. L.A.M. Marks

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Paranimfen:

Maria Isabel Patino

Ke Ren

(8)

Table of Contents

chapter 1

1.1 General introduction

Carbon quantum dots derived from different carbon sources for antibacterial application

1.2 Aim of the thesis

1

chapter 2

Enhanced bacterial killing by vancomycin in

staphylococcal biofilms disrupted by novel,

DMMA-modified carbon dots depends on EPS

production

Yanyan Wu, Henny C. van der Mei, Henk J. Busscher, Yijin Ren

(Colloids and Surfaces B: Biointerfaces 2020; 193, 111114)

29

chapter 3

Inheritance of physico-chemical properties by

carbon quantum dots derived from pyrolytically

carbonized bacterial sources

Yanyan Wu, Hao Wei, Henny C. van der Mei, Joop de Vries, Henk J. Busscher, Yijin Ren

(Submitted to Journal of Colloid and Interface Science)

55

chapter 4

Ciprofloxacin efficacy against infectious

biofilms pre-exposed to “probiotic” or

“pathogenic” carbon quantum dots

Yanyan Wu, Henny C. van der Mei, Henk J. Busscher, Yijin Ren

(Submitted to Advanced Functional Materials)

83

chapter 5

General discussion

105

Summary

111

Samenvatting

115

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