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Magnetic tweezers based force spectroscopy studies of the structure and dynamics of nucleosomes and chromatin Kruithof, M.C.

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Magnetic tweezers based force spectroscopy studies of the structure and dynamics of nucleosomes and chromatin

Kruithof, M.C.

Citation

Kruithof, M. C. (2009, October 1). Magnetic tweezers based force spectroscopy studies of the structure and dynamics of nucleosomes and chromatin. Retrieved from https://hdl.handle.net/1887/14030

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/14030

Note: To cite this publication please use the final published version (if

applicable).

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Curriculum Vitae

Maarten Kruithof was born in  in Andernach, Germany. In  he finished his second education at the Rijnlands Lyceum in Oegstgeest. In that same year he started his studies in applied physics at the University of Technology in Delft. After finishing his undergraduate studies he started working on the conductive properties of glass nanofluidic channels under the mentorship of Prof. Dr. C. Dekker. He also spend several months in the group of Prof.

Dr. G. Whitesides at Harvard in Cambridge, USA. Here he created a system for microfluidic valving. in  he received his MSc at the University of Technology in Delft.

From June  till September  he was affiliated to Leiden University as a PhD student.

Here he joined the research group of Dr. Ir. J van Noort where he worked on magnetic tweezers based studies on nucleosomes and chromatin. During this period he was responsible for or- ganising the biweekly seminar of the biophysics and monos groups. Furthermore, he lectured in the exercise classes belonging to an undergraduate course in classical mechanics.

From November  he he joined the computer vision and statistics group of TNO Industry and technology where he does research on the analyses of camera images .

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List of Publications

Surface-charge-governed ion transport in nanofluidic channels, D. Stein, M. Kruithof and C.

Dekker, Physical Review Letters, , (): 

Torque-actuated valves for microfluidics, D.B. Weibel, M. Kruithof, S. Potenta, S.K. Sia, A. Lee, G.M. Whitesides, Analytical Chemistry, , (): -

Subpiconewton Dynamic Force Spectroscopy Using Magnetic Tweezers, M. Kruithof, F. Chien, M. de Jager and J. van Noort, Biophysical Journal, , (): -

Hidden Markov Analysis of Nucleosome Unwrapping Under Force, M. Kruithod and J. van Noort, accepted for publication in Biophysical Journal, 

Single molecule force spectroscopy reveals a highly compliant helical folding for the  nm chromatin fiber, M. Kruithof, F. Chien, A. Routh, C. Logie, D. Rhodes and J. van Noort, Nature Structural and Molecular Biology, , May: online

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