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Developmental regulation and evolution of cAMP signalling in Dictyostelium

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(1)Developmental regulation and evolution of cAMP signalling in Dictyostelium Alvarez-Curto, E.. Citation Alvarez-Curto, E. (2007, October 23). Developmental regulation and evolution of cAMP signalling in Dictyostelium. Retrieved from https://hdl.handle.net/1887/12476 Version:. Not Applicable (or Unknown). License: Downloaded from:. https://hdl.handle.net/1887/12476. Note: To cite this publication please use the final published version (if applicable)..

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(8) .   . Developmental regulation and evolution of cAMP signalling in Dictyostelium. Proefschrift. ter verkrijging van de graad van Doctor aan de Universiteit Leiden, op gezag van de Rector Magnificus prof. mr. P.F. van der Heijden, volgens besluit van het College voor Promoties te verdedigen op dinsdag 23 oktober 2007 klokke 13.45 uur door. Elisa Álvarez Curto geboren te Valladolid, Spanje in 1975. Elisa Álvarez-Curto.

(9) Promotiecommissie. Promotores:. Prof. Dr. P.J.J. Hooykaas Prof. Dr. P. Schaap (University of Dundee, Verenigd Koninkrijk). Referent:. Dr. M. Wang. Overige leden:. Prof. Dr. P.M. Brakefield Prof. Dr. A.J. Durston Prof. Dr. J. Memelink Prof. Dr. H.P. Spaink.

(10) To Phil, always A Mamá, siempre.

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(12) Contents. Chapter Title General Introduction. Page 9. Adenylyl cyclase G triggers prespore differentiation in Dictyostelium slugs. 25. Pharmacological profiling of adenylyl cyclases ACA, ACB and ACG. 39. Characterization of an adenosine kinase in Dictyostelium. 53. Molecular phylogeny and evolution of morphology in the social amoebas. 67. Evolution of cAMP-based chemoattraction in the social amoebas. 85. Discussion. 97. Samevatting (Summary for non-biologists). 107. Curriculum Vitae. 115. Publications. 116. Dankwoord (Acknowledgements). 117.

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