Zebrafish embryos and Larvae : a new generation of disease model and drug screens
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License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden Downloaded.
Here, we review the use of zebrafish embryos and early larvae in applied biomedical research, using selected cases.. We look at the use of zebrafish embryos as disease models,
Zebrafish embryos with intact chorion at prim-6 were divided into the following treatment h (ii) vehicle only for 1 h (iii) 10% ethanol for 1 h followed by three washes with
One study has reported, using 18 toxic compounds, that toxicity in zebrafish was well-correlated with values reported from rodent studies [206].. The zebrafish embryo system has
We were able to divide the tested compounds into three groups based on the effects seen in the zebrafish challenge phase: those that show similar locomotor effects in
Bilotta J, Barnett JA, Hancock L, Saszik S (2004) Ethanol exposure alters zebrafish development: a novel model of fetal alcohol syndrome.. Loucks E, Carvan MJ, III
We argued in this thesis that zebrafish embryos and early larvae can serve as invaluable screening tools in the pre-regulatory, preclinical phase of drug discovery and drug safety
Wij laten zien dat het zebravis embryo/larve gebruikt kan worden in de high-throughput gedrags screening van verschillende stoffen. We hebben 60 water-oplosbare toxische
