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University of Groningen Fluorescent Nanodiamonds as Free Radical Sensors in Aging Yeast Cells van der Laan, Kiran

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University of Groningen

Fluorescent Nanodiamonds as Free Radical Sensors in Aging Yeast Cells

van der Laan, Kiran

DOI:

10.33612/diss.112906297

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2020

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

van der Laan, K. (2020). Fluorescent Nanodiamonds as Free Radical Sensors in Aging Yeast Cells: a baker’s yeast response to small diamonds with great potential!. Rijksuniversiteit Groningen.

https://doi.org/10.33612/diss.112906297

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 Yeast cells need help to internalize FNDS, which we are able to give them, by applying an optimized chemical transformation protocol that is highly efficient. (this thesis)

 Both the presence of FNDs as the uptake protocol itself do not cause major fatal effects to the yeast cells. (this thesis)

 Once internalized in chronological aging yeast cells, FNDs are preferentially located at membrane-enclosed organelles. (this thesis)

 Cell viability has many different faces.

 Any kind of stress arises from a disturbance of the balance.

 While in microscopy we aim to zoom in to understand certain things, in life it often helps to take some distance to get a clearer view.

 The closer one gets to finding an answer, the more new questions start to appear.

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