Cover Page
The handle
http://hdl.handle.net/1887/66888
holds various files of this Leiden University
dissertation.
Author: Mastboom, M.J.L.
PROEFSCHRIFT
ter verkrijging van
de graad van Doctor aan de Universiteit van Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op dinsdag 13 november 2018
Cover design and thesis layout Lisanne de Koster ISBN 978-94-9301-479-4
Printed by Gildeprint, Enschede, the Netherlands Copyright © 2018 by Monique Mastboom
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means without permission in writing from the author. The copyright of the articles has been transferred to the respective journals.
The conduction of the research included in this thesis was carried out at the Department of Orthopaedics of the Leiden University Medical Centre, Leiden, the Netherlands.
Promotores
Prof. dr. P.D.S. Dijkstra Prof. dr. A.J. Gelderblom
Co-promotor
Dr. M.A.J. van de Sande
Leden promotiecommissie
Prof. dr. J.V.M.G. Bovee
General introduction and outline of this thesis
Incidence
Higher incidence rates than previously known in Tenosynovial Giant Cell Tumours
M.J.L. Mastboom, F.G.M. Verspoor, A.J. Verschoor, D. Uittenbogaard, B. Nemeth, W.J.B. Mastboom, J.V.M.G. Bovee, P.D.S. Dijkstra, H.W.B. Schreuder, H. Gelderblom, M.A.J. van de Sande, TGCT study group.
Acta Orthop. 2017 Dec;88(6):688-694
Diagnostics
Does CSF1 over-expression or rearrangement influence biological behaviour in Tenosynovial Giant Cell Tumours of the knee?
M.J.L. Mastboom, D.M. Hoek, J.V.M.G. Bovee, M.A.J. van de Sande*, K. Szuhai* (*Shared last authorship).
Histopathology 2018 Aug. doi: 10.1111/his.13744
Disease severity
Severity classification of Tenosynovial Giant Cell Tumours on MR imaging
M.J.L. Mastboom*, F.G.M. Verspoor*, D.F. Hanff, M.G.J. Gademan, P.D.S. Dijkstra, H.W.B. Schreuder, J.L. Bloem, R.J.P. van der Wal, M.A.J. van de Sande (*Shared first authorship).
Surg Oncol. 2018 Sept;27(3):544-550
Hormones
Can increased symptoms of Tenosynovial Giant Cell Tumours during pregnancy be explained by a change in female sex hormones?
M.J.L. Mastboom, F.G.M. Verspoor, R. Planje, H.W.B. Schreuder, M.A.J. van de Sande.
114
134
162
190
Chapter 6.
Chapter 7.
Chapter 8.
Chapter 9.
ChildrenTenosynovial Giant Cell Tumours in children: a similar entity compared with adults
M.J.L. Mastboom, F.G.M. Verspoor, D. Uittenbogaard, G.R. Schaap, P.C. Jutte, H.W.B. Schreuder, M.A.J. van de Sande.
Clin Orthop Relat Res. 2018 Sept;476(9):1803-1812
Localized-TGCT
Surgical treatment of localized-type Tenosynovial Giant Cell tumours of large joints
M.J.L. Mastboom, E. Staals, F.G.M. Verspoor, A.J. Rueten-Budde, S. Stacchiotti, E. Palmerini, G.R. Schaap, P.C. Jutte, W. Aston, A. Leithner, D. Dammerer, A. Takeuchi, Q. Thio, X. Niu, J.S. Wunder, TGCT study group, M.A.J. van de Sande.
Submitted
Diffuse-TGCT
Outcome of surgical treatment for patients with diffuse-type Tenosynovial Giant Cell Tumours
M.J.L. Mastboom, E. Palmerini, F.G.M. Verspoor, A.J. Rueten-Budde, S. Stacchiotti, E. Staals, G.R. Schaap, P.C. Jutte, W. Aston, H. Gelderblom, A. Leithner, D. Dammerer, A. Takeuchi, Q. Thio, X. Niu, J.S. Wunder, TGCT study group, M.A.J. van de Sande.
Submitted
Treatment
Long-term efficacy of imatinib mesylate in patients with advanced Tenosynovial Giant Cell Tumour
M.J.L. Mastboom*, F.G.M. Verspoor*, G. Hannink, R.G. Maki, A. Wagner, E. Bompas, J. Desai, A. Italiano, B.M. Seddon, W.T.A. van der Graaf, J.Y. Blay, M. Brahmi, L. Eberst, S. Stacchiotti, O. Mir, M.A.J. van de Sande, H. Gelderblom, P.A. Cassier (*Shared first authorship).
Quality of life
The effect of surgery in Tenosynovial Giant Cell Tumours as measured by patient reported outcomes on quality of life and joint function
M.J.L. Mastboom*, F.G.M. Verspoor*, G. Hannink, W.T.A. van der Graaf, M.A.J. van de Sande, H.W.B. Schreuder (*Shared first authorship).
Accepted in Bone Joint J
Impact on daily living
The patient perspective on the impact of Tenosynovial Giant Cell Tumours on daily living: Crowdsourcing study on physical function and quality of life
M.J.L. Mastboom, R. Planje, M.A.J. van de Sande.
Interact J Med Res. 2018 Feb 23;7(1):e4.
Limb amputation
Limb amputation after multiple treatments of Tenosynovial Giant Cell Tumour: Series of 4 Dutch cases
M.J.L. Mastboom, F.G.M. Verspoor, H. Gelderblom, M.A.J. van de Sande.
Case Rep Orthop. 2017;7402570.
Summary of this thesis
