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Apoptin : oncogenic transformation & tumor-selective apoptosis Zimmerman, R.M.E.

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Apoptin : oncogenic transformation & tumor-selective apoptosis

Zimmerman, R.M.E.

Citation

Zimmerman, R. M. E. (2011, December 21). Apoptin : oncogenic transformation & tumor- selective apoptosis. BOXPress, Oisterwijk. Retrieved from

https://hdl.handle.net/1887/18268

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/18268

Note: To cite this publication please use the final published version (if applicable).

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Stellingen

Behorende bij het proefschrift

Apoptin - Oncogenic Transformation & Tumor-selective Apoptosis

1. Apoptin is a specific killer of cancer and transformed cells (this thesis; Agraris, et al., 2011; Grimm and Noteborn, 2010)

2. FAM96B is an essential protein, required for proper sister chromatid cohesion and chromosome segregation

(this thesis; Ben Arroya, et al., 2008; Ito, et al., 2010)

3. Apoptin senses DNA damage (this thesis; Kurcharski et al, 2011)

4. PP2A is apoptin’s normal-cell-specific phosphatase (this thesis)

5. Through manipulation of their (epi)genetic codes, as well as their environment, cancer cells have become masters of their own destinies.

6. It is indeed naïve to search for a magical bullet cure for cancer. By combining the properties of various PKTC, we will instead be able to build a magical cluster bomb.

7. In the long run, it doesn’t matter where exactly you publish your data: if it’s any good, it will be picked up anyway, and if not, the less fuss you made about it, the better

(Kym Nasmyth, EMBO Meeting 2009)

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8. Research shows that the quality of the supervisor-PhD student relationship is of major imporance for the success of a PhD project (Mainhard, et al., 2009)

9. Faith is the realization of what is hoped for and evidence of things not seen

(Hebrew 11:1)

10. If you’re not working on a Sunday, you’re not working on something important

(Jim Watson, Lund Meeting on PKTC 2009)

11. Give a girl the right pair of shoes, and she can conquer the world (attributed to both Bette Midler and Marylin Monroe, either way, it was a fabulous woman)

12. There’s no place like home (the Wizard of Oz)

Rhyenne M.E.Zimmerman Leiden 2011

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