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Mood related insights : functional and structural MRI studies in depression and anxiety disorders

Tol, M.J. van

Citation

Tol, M. J. van. (2011, May 26). Mood related insights : functional and structural MRI studies in depression and anxiety disorders. Retrieved from https://hdl.handle.net/1887/17672

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/17672

Note: To cite this publication please use the final published version (if

applicable).

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MOOD RELATED INSIGHTS

FUNCTIONAL AND STRUCTURAL MRI STUDIES IN DEPRESSION AND ANXIETY DISORDERS

MARIE-JOSÉ VAN TOL

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Marie-José van Tol

Mood Related Insights: functional and structural MRI studies in depression and anxiety disorders

cover design and illustrations: David Kops

Print: GVO drukkers & vormgevers B.V. | Ponsen & Looijen, Ede The Netherlands

The infrastructure for the NESDA study (www.nesda.nl) is greatly acknowledged.

The NESDA infrastructure is funded through the Geestkracht program of the Netherlands Organisation for Health Research and Development (Zon-Mw, grant number 10-000-1002) and is supported by participating universities and mental health care organizations (VU University Medical Center, GGZ inGeest, Arkin, Leiden University Medical Center, GGZ Rivierduinen, University Medical Center Groningen, Lentis, GGZ Friesland, GGZ Drenthe, Scientific Institute for Quality of Healthcare (IQ healthcare), Netherlands Institute for Health Services Research (NIVEL) and Netherlands Institute of Mental Health and Addiction (Trimbos Institute).

© 2011 M.J. van Tol, Leiden, The Netherlands

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MOOD RELATED INSIGHTS

FUNCTIONAL AND STRUCTURAL MRI STUDIES IN DEPRESSION AND ANXIETY DISORDERS

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op donderdag 26 mei 2011

klokke 13.45 uur

door

Marie-José van Tol geboren te Amstelveen

op 25 December 1980

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Promotiecommissie

Promotores: Prof. dr. F.G. Zitman Prof. dr. M.A. van Buchem

Prof. dr. D.J. Veltman (Vrije Universiteit) Copromotor: Dr. N.J.A. van der Wee

Overige leden: Prof. dr. S.A.R.B. Rombouts Prof. dr. B. Hommel

Prof. dr. A.H. Schene (Universiteit van Amsterdam)

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INDEX

General Introduction

Regional brain volume in depression and anxiety disorders

Emotional word encoding and recognition in depression and anxiety disorders

Functional MRI correlates of visuospatial planning in outpatient depression and anxiety

Whole brain functional connectivity during emotional word classification in medication free Major Depressive Disorder

Reduced medial prefrontal cortex volume in adults reporting childhood emotional maltreatment

Affective personality traits are linked to volume of the orbitofrontal cortex and amygdala

Summary, general discussion, & future perspectives

Appendix Reference list Abbreviations

Nederlandse samenvatting List of publications Curriculum vitae

9 29

49

77

99

115

131 139

169 173 197 199 209 213 Chapter 1

Chapter 2 Chapter 3

Chapter 4

Chapter 5

Chapter 6

Chapter 7

Chapter 8 Chapter 9

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