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The focus of his PhD was to discover if protein-tyrosine phosphatases became oxidized following zebrafish caudal fin amputation, and to study the role of protein-tyrosine

Differential oxidation of protein tyrosine phosphatases occurs following zebrafish caudal fin amputation, and there is a differential requirement for protein-tyrosine

Our assays involve: (i) systemic or local administration of a test compound or drug to zebrafish in vivo; (ii) the subsequent detection or "readout" of a defined

After 9 weeks of treatment, liver samples were collected and RT-qPCR was used to measure mRNA expression of genes involved in (A) the classical bile acid (BA) synthesis pathway,

In the present study, we provide evidence that short-term cooling, the most important physiological activator of BAT, increases serum concentration of TG and apoB due to the an

Hematopoietic IL-37 expression does not affect metabolic parameters Human IL-37 was selectively expressed in hematopoietic cells, including macrophages, of atherosclerosis-prone

In summary, our results do not support a fundamental role for Dectin-2 in inflammation or atherosclerotic lesion development, while they show that deletion of hematopoietic

Hematopoietic deletion of the downstream master regulator of the CLR family CARD9 also does not influence atherosclerotic lesion size, but does appear to moderately impact