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University of Groningen

Adaptation after mild traumatic brain injury

van der Horn, Harm

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

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Publication date: 2017

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

van der Horn, H. (2017). Adaptation after mild traumatic brain injury: The role of structural and functional brain networks. Rijksuniversiteit Groningen.

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The Role of Structural and Functional Brain Networks

Hans van der Horn

ADAPTATION

A F T E R M I L D T R AU M AT I C

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ISBN (e-book): 978-90-367-9672-9 ISBN (printed book): 978-90-367-9673-6

Cover design: Kalle Wolters (kallixters@gmail.com)

Layout: Rikkert Veltman Media Producties (rikkert.veltman@gmail.com) Printed by Ipskamp Printing

© Hans van der Horn. All rights reserved. No part of this publication may be reproduced, stored in, or introduced into a retrieval system, or transmitted in any form or by any means (electronic, mechanical, photocopying, recording, or otherwise) without prior permission from the author.

This research was financially supported by the Dutch Brain Foundation (Hersenstichting Nederland).

Publication of this dissertation was financially supported by the University Medical Center Groningen (UMCG) and the University of Groningen.

Conference attendendances were financially supported by the Research School of Behavioral and Cognitive Neurosciences (BCN).

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Adaptation After Mild Traumatic

Brain Injury

The Role of Structural and Functional Brain Networks

Proefschrift

door

Harm Jan van der Horn

geboren op 23 juli 1985 te Groningen

ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op woensdag 21 juni 2017 om 12.45 uur

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Promotores

Prof. dr. J. van der Naalt Prof. dr. J.M. Spikman Beoordelingscommissie Prof. dr. H.P.H. Kremer Prof. dr. R.P.C. Kessels Prof. dr. ir. N.M. Maurits

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Paranimfen M.E. Scheenen M.E. de Koning

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General Introduction

Review:

Brain Networks Subserving Emotion Regulation and Adaptation After Mild Traumatic Brain Injury (J Neurotrauma 2016 Jan 1;33(1):1-9)

Structural MRI studies:

Clinical Relevance of Microhemorrhagic Lesions in Subacute Mild Traumatic Brain Injury (submitted)

Altered Wiring of the Human Structural Connectome in Adults with Mild Traumatic Brain Injury (J Neurotrauma 2017 Mar 1;34(5):

1035-1044)

Functional MRI studies:

Post-concussive Complaints After Mild Traumatic Brain Injury Associated with Altered Brain Networks During Working Memory Performance (Brain Imaging Behav. 2016 Dec 10(4):1243-1253) Brain Network Dysregulation, Emotion and Complaints After Mild Traumatic Brain Injury (Hum Brain Mapp. 2016 Apr;37(4):1645-54) Graph Analysis of Functional Brain Networks in Mild Traumatic Brain Injury (PLoS One 2017 Jan 27;12(1):e0171031)

The Default Mode Network as a Biomarker of Persistent Complaints After Mild Traumatic Brain Injury: A Longitudinal fMRI Study

(submitted)

General Discussion and Future Perspectives References

Nederlandse samenvatting (Summary in Dutch) Dankwoord (Acknowledgements) List of Publications Curriculum Vitae

Contents

1. 2. 3. 4. 5. 6. 7. 8. 9. 9 15 31 39 65 91 109 129 149 157 185 191 197 201

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