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University of Groningen

The art of balance

Hessels, Lara

DOI:

10.33612/diss.101445743

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date:

2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Hessels, L. (2019). The art of balance: acute changes in body composition during critical illness.

Rijksuniversiteit Groningen. https://doi.org/10.33612/diss.101445743

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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The art of balance

Acute changes in body composition

during critical illness

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Paranimfen

F. Doesburg

L. Reinke

Publication of this thesis was financially supported by the University

Medical Centre Groningen, the University of Groningen, and the

Gradu-ate School GUIDE of the University of Groningen.

Cover design and lay out by Ellen Beck

Printed by Ipskamp Printing

ISBN 978-94-034-2054-7 (printed version)

ISBN 978-94-034-2055-4 (digital version)

© Copyright L. Zwakman-Hessels, 2019

All rights reserved. No part of this thesis may be reproduced, stored in

a retrieval system, or transmitted in any form or by any means, without

prior written permission of the author, or when appropriate, of the

pub-lishers of the publications included in this thesis.

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The art of balance

Acute changes in body composition during critical illness

Proefschrift

Ter verkrijging van de graad van doctor aan de

Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. C. Wijmenga

en volgens besluit van het college voor promoties

De openbare verdediging zal plaatsvinden op

woensdag 27 november 2019 om 16:15 uur

door

Lara Hessels

Geboren op 9 augustus 1991

te Zwolle

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Promotores

Dr. M.W.N. Nijsten

Prof. dr. A.M.G.A. de Smet

Copromotor

Dr. M. Zeillemaker-Hoekstra

Beoordelingscommissie

Prof. dr. R. Bellomo

Prof. dr. R.P. Pickkers

Prof. dr. S.P. Berger

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Table of contents

CH1 P9

CH2 P18

CH3 P36

The relationship between serum potassium, potassium variability and in-hospital mortality in critically ill patients and a before-after analysis on the impact of computer-assisted potassium control

Computer-guided normal-low versus normal-high potassium control after cardiac surgery: no impact on atrial fibrillation or atrial flutter General introduction

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CH4 P52

CH7 P96

CH10 P176

CH5 P70

CH8 P116

CH11 P196

CH6 P88

CH9 P136

CH12 P202

CH13 P213

Opposite acute potassium and sodium shifts during transplantation of hypothermic machine

perfused donor livers Estimation of sodium and chloride storage in critically ill patients: a balance study

Summary

Hypothesis: angiotensin and aldosterone inhibitors help improve outcome in chronic heart failure because potassium sparing preserves skeletal muscle mass

Urinary creatinine excretion is related to short-term and long-term mortality in critically ill patients General discussion • Nederlandse samenvatting (p213) • Dankwoord (p218) • Curriculum vitae (p222) • List of publications (p224) Postoperative fluid retention

after heart surgery is accompanied by a strongly positive sodium balance and a

negative potassium balance Long-term changes in dysnatremia incidence in the ICU: a shift from hyponatremia to hypernatremia

Time courses of urinary creatinine excretion, measured creatinine clearance and estimated glomerular filtration rate over 30 days of ICU admission

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