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A new mechanism of antimalarial drug resistance regulated at the epigenetic level
Mira Martínez, S.
2018
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Mira Martínez, S. (2018). A new mechanism of antimalarial drug resistance regulated at the epigenetic level.
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LIST OF ABBREVIATIONS
5-ALA 5-aminolevulinic acidACT Artemisinin-based combination therapy ART Artemisinin
AQ Amodiaquine
AZI Azithromycin BS Blasticidine S BSD Blasticidine S
CLAG Cytoadherence link asexual gene
CQ Chloroquine
DHODH Dihydroorotate dehydrogenase DHPS Dihydropteroate synthase EPCR Endothelial protein C receptor FOSMI Fosmidomycin
G6PD Glucose-6-phosphate dehydrogenase
gDNA Genomic DNA
GNI Gross National Income HbC Hemoglibne C
HbS Hemoglibne S
HP1 Heterochromatin protein 1 HVR Hypervariable region
ICAM1 Intercellular adhesion molecule 1 IPT Intermittent preventive treatment
IPTi Intermittent preventive treatment in infancy
IPTp Intermittent preventive treatment in pregnant women
IPT-SP Intermittent preventive treatment with sulfadoxine-pyrimethamine IRB Institutional Review Board
ISGlobal Barcelona Institute for Global Health ITM Institute of Tropical Medicne, Antwerp K13 PF3D7_1343700 kelch propeller domain LAMP Loop-mediated isothermal amplification LEUP Leupeptine
LM Light mycroscopy
LUM Lumefantrine
LysoPC Lysophosphatidylcholine
malERA Malaria eradication research agenda MDA Mass drug administriation
MDG Millennium Development Goals MDR-TB Mmultidrug-resistance tuberculosis MMV Medicines for Malaria Venture MOI Multiplicity of infection
MQ Mefloquine
NAT Nucleic acid tests ncRNA Non-conding RNA
NGS Next-generation sequencing NIH National Institutes of Health NO Nitric oxide
NPP New Permeation pathways
NtCR N-terminal paralogue-specific conserved region PCR Long polymerase chain reaction
PfCRT P. falciparum CQ resistance transporter
PfEMP1 P. falciparum erythrocyte membrane protein-1 PfHRP2 P. falciparum histidine-rich protein 2
PfMDR1 P. falciparum multidrug resistance transporter PfPI3K P. falciparum phosphatidylinositol-3-kinase PI3P PI3-phosphate
PPIX Protoporphyrin IX
PSAC Plasmodial Surface Anion Channel
PYR Pyrimethamine
qPCR Quantitative-PCR RBC Red blood cell
RDT Rapid diagnostic tests RSA Ring-stage survival assay RT-PCR Real Time - PCR
SDX Sulfadoxine
SMC Seasonal malaria chemoprevention SNP Single nucleotide polymorphisms SP Sulfadoxine-pyrimethamine
T3 Albitiazolium
TF Transcription factor WHO World Health Organization
