Cover Page
The handle http://hdl.handle.net/1887/136093 holds various files of this Leiden University dissertation.
Author: Valk, M.J.M. van der
Title: Locally advanced rectal cancer: New insights for a tailored approach Issue date: 2020-09-03
Locally advanced rectal cancer New insights for a tailored approach
Maxime Johanna Maria van der Valk
through the Bas Mulder award granted to Dr. Denise Hilling
Financial support for printing of this thesis by Erbe, Quest Medical Imaging and Chipsoft is gratefully acknowledged.
Locally advanced rectal cancer New insights for a tailored approach
Proefschrift
Ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op donderdag 3 september 2020
klokke 13.45 uur
door
Maxime Johanna Maria van der Valk geboren te Nijmegen
in 1988
Co-promotor Dr. D.E. Hilling Promotiecommissie Prof. dr. H. Putter Prof. dr. C.A.M. Marijnen
Prof. dr. H. Rutten Maastricht Universitair Medisch centrum, Catharina ziekenhuis Prof. dr. G.A.P. Hospers Universitair Medisch Centrum Groningen
Dr. J. Melenhorst Maastricht Universitair Medisch centrum
CONTENTS
Chapter 1 Introduction and thesis outline
Chapter 2 Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicenter registry study
Chapter 3 Quality of life after curative resection for rectal cancer in patients treated with adjuvant chemotherapy compared with observation:
results of the randomized phase III SCRIPT trial
Chapter 4 Compliance and tolerability of short-course radiotherapy followed by preoperative chemotherapy and surgery for high-risk rectal cancer:
results of the international randomized RAPIDO-trial
Chapter 5 Importance of patient reported and clinical outcomes for patients with locally advanced rectal cancer and their treating physicians. Do clini- cians know what patients want?
Chapter 6 Disqualification of the Neoadjuvant Rectal (NAR) score based on data of 6596 from the Netherlands Cancer Registry
Chapter 7 Summary and general discussion
Appendix Nederlandse samenvatting Publicatielijst
Curriculum vitae Dankwoord
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