Long-term outcome of rectal cancer treatment
Lange, M.M.
Citation
Lange, M. M. (2009, February 18). Long-term outcome of rectal cancer treatment. Retrieved from https://hdl.handle.net/1887/13523
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
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Long-term outcome of rectal cancer treatment
Marilyne Lange
Cover: Le Juste Milieu (2008) by GJD van Acker & JFM Lange - Studio J.C. Sacque.
© 2009, M.M. Lange ISBN 978-90-8559-480-2
Printed by Optima Grafische Communicatie, Rotterdam
The printing of this thesis was sponsored by Coloplast BV, EuroTec BV, Braun Medical BV, Amgen BV, Welmed BV, Novartis Oncology, Nycomed Nederland BV, Covidien Nederland BV, Olympus Nederland BV.
Long-term outcome of rectal cancer treatment
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties
te verdedigen op woensdag 18 februari 2009
klokke 15.00 uur
door
Marilyne Michèle Lange geboren te Uccle (België)
in 1983.
PROMOTIECOMMISSIE
Promotor: Prof. Dr. C.J.H. van de Velde
Referent: Prof. Dr. Th. Wiggers (Universitair Medisch Centrum Groningen)
Overige leden: Prof. Dr. C.A.M. Marijnen
Dr. H.J. Rutten (Catharina ziekenhuis, Eindhoven) Prof. Dr. R.A.E.M. Tollenaar
Aan mijn ouders
7
CONTENTS
Chapter 1 General introduction and outline 9
Chapter 2 One hundred years of curative surgery for rectal cancer:
1908-2008
Eur J Surg Oncol. In press
19
Chapter 3 Level of arterial ligation in rectal cancer surgery: low tie preferred over high tie. A review.
Dis Colon Rectum. 2008 July; 51(7): 1139–1145.
37
Chapter 4 Risk factors for sexual dysfunction after rectal cancer treat- ment
Eur J Ca. In press
53
Chapter 5 Urinary dysfunction after rectal cancer treatment is mainly caused by surgery
Br J Surg. 2008 Aug;95(8):1020-8.
73
Chapter 6 Risk factors for faecal incontinence after rectal cancer treatment
Br J Surg. 2007 Oct;94(10):1278-84.
91
Chapter 7 Faecal and urinary incontinence after multimodality treat- ment of rectal cancer
PLoS Med. 2008 Oct 7;5(10):e202.
107
Chapter 8 Causes of faecal and urinary incontinence after total me- sorectal excision for rectal cancer based on cadaveric surgery J Clin Oncol. 2008 Sep 20;26(27):4466-72.
119
Chapter 9 Leukocyte depletion of perioperative blood transfusion does not affect long-term survival and recurrence in gastrointesti- nal cancer patients
Submitted
133
Chapter 10 Discussion and future perspectives 147
Contents
8
Summary 163
Nederlandse samenvatting 169
Curriculum vitae 175
Nawoord 177
