Molecular pathology of colorectal cancer predisposing syndromes Puijenbroek, M. van

Genotyping of the c.827AC Polymorphism in PTPRJ Using the MassEXTEND Analysis The c.827AC SNP in PTPRJ was genotyped in 156 healthy blood donors and normal DNA from 222 patients

To evaluate the frequency of the CHEK2  1100delC mutation in a well-defined familial colorectal cancer cohort, and to study the possible role of five CHEK2 germline variants

We characterized chromosomal instability (physical loss, gain, and cnLOH) and micro- satellite instability in carcinomas from Lynch syndrome patients with pathogenic MMR

Tumors from individuals with an early onset in addition to clustering of CRC in the family are analyzed for microsatellite instability and expression of the mismatch repair

Het onderliggende lijden wordt verklaard door twee kiembaan mutaties in MUTYH, geërfd van beide ou- ders (een autosomaal recessief overervings patroon). Voor veel individuen

De KRAS2 c.34 G>T analyse op formaline gefixeerd in paraffine ingebed tumor weefsel maakt het mogelijk (atypische) MAP families te identificeren.. Het dragen van meerdere

Peripheral blood cells were stained with HLA-A2.1 tetramers containing the tyrosinase368–376 peptide followed by staining with a panel of lineage antibodies, as described in

Blades and blade fragments seem to have been especially used for longitudinal motions, mainly on plant material (7/12). Flake and flake fragments are used in different motions on