Kassiani Kytidou
Propositions:
1. The development of therapies that specifically target affected organs in Fabry disease might be a better way to treat specific symptoms.
2. Studying plant glycosidases expands the knowledge of human homologues as well (This thesis chapter 4, 5).
3. Dimerization of human alpha-galactosidase A might be of great importance for its stability.
4. Application of activity-based probes in diagnosis of lysosomal storage disorders warrants consideration (This thesis chapter 7).
5. N-linked glycans of recombinant proteins can either be a burden or a blessing for enzyme replacement therapy.
6. Immune response against plant specific N-linked glycans might not be as common as initially thought.
7. Despite major homology, glycosidases from different species may differ in features and potential applications (This thesis chapter 4, 5).
8.To pursue a scientific career, young mothers should be more actively supported.
9. Some plant glycosides are healthy ingredients of our daily diet that are taken for granted (This thesis chapter 2).
10. Success in science does not come without a bit of luck.
