Site-selective incorporation of alpha- and beta-amino acid derivatives : towards new gramicidin S-based bactericides

A second independent series of peptides was prepared as well in which GS and the known antibiotic cyclic dodecameric peptide gratisin were central.. Gratisin is known to have

For this purpose Gramicidin S was chosen and as outlined in Chapters 2 and 3 of this Thesis the D -phenylalanine in the turn appeared to be a suitable position to introduce

Deze modificaties bleken weinig invloed te hebben op de structuur, maar er werd geen derivaat gevonden dat sterkere activiteit vertoonde dan GS zelf, noch een peptide dat aanzienlijk

Na het behalen van het doctoraal examen in 2006 werd begonnen met het in dit proefschrift beschreven onderzoek als AIO in de groep van Prof.. Hermen Overkleeft en

Site-selective incorporation of alpha- and beta- amino acid derivatives : towards new gramicidin S-based bactericides.. Retrieved

Peripheral blood cells were stained with HLA-A2.1 tetramers containing the tyrosinase368–376 peptide followed by staining with a panel of lineage antibodies, as described in

Blades and blade fragments seem to have been especially used for longitudinal motions, mainly on plant material (7/12). Flake and flake fragments are used in different motions on

This shape also occurs in the combination artefacts (see below). The shape is the result of intensive use in a repetitive abrasive motion, carried out from different angles. In