Novel Pathways in Cholesterol Metabolism

In chapter 5 it was proposed that the difference in dyslipidemia and body weight between responders and non-responders is due to a combination of decreased fat

By feeding these mice with a humanized lipid profile a diet relatively rich in fat and cholesterol, and by monitoring how the mice subsequently increase in body weight,

Furthermore, we found that the increased fecal fat excretion was associated with decreased fecal bile acid excretion, suggesting that a decrease in bile acid production

If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.. Downloaded

Cyp7a1 catalyzes the first and rate-limiting step in the conversion of cholesterol into bile acids in mice (30); however, decreased Cyp7a1 expression in Washc1 depleted

tail of LDLR or LRP1 and, together with DSCR3/VPS35C, retrieves the receptors from lysosomal degradation after endocytosis. The WASH complex is recruited to the endosomes, which

We focused specifically on the contribution of the endosomal network to cholesterol metabolism and atherosclerosis by studying the molecular regulation of the

tail of LDLR or LRP1 and, together with DSCR3/VPS35C, retrieves the receptors from lysosomal degradation after endocytosis. The WASH complex is recruited to the endosomes, which