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University of Groningen Surface supported dynamic combinatorial chemistry for biomacromolecule recognition Miao, Xiaoming

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University of Groningen

Surface supported dynamic combinatorial chemistry for biomacromolecule recognition

Miao, Xiaoming

DOI:

10.33612/diss.99692802

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date: 2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Miao, X. (2019). Surface supported dynamic combinatorial chemistry for biomacromolecule recognition. University of Groningen. https://doi.org/10.33612/diss.99692802

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Propositions

Accompanying the dissertation

Xiaoming Miao

1. Although complexity is at odds with traditional chemistry, it acts as a bridge that connects chemistry with other research disciplines like materials science and biology.

2. The challenge in the replicative growth of populations of sequence polymers resides not so much in the copying step, but rather in enabling continued population growth.

3. As the exchange of matter and/or energy between the system and its surroundings are necessary for making synthetic life, non-equilibrium conditions are essential.

4. Lack of knowledge and understanding currently limits rational design in systems chemistry.

5. In the field of chemistry solving problems experimentally is more efficient than solving them theoretically.

6. In biology, chemical reactions have to be efficient with respect to selectivity and reactivity since the probability of collision between reactants is extremely low.

7. Dendrimers represent an ideal platform to study multivalent surface recognition of biomolecules due to the presence of different functional groups in high density and their simplicity.

8. Systems chemists should embrace engineering because synthesizing a system (a new trend in chemistry) requires the knowledge of engineering.

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