Cover Page
The following handle holds various files of this Leiden University dissertation:
http://hdl.handle.net/1887/79262
Author: Gelder, J. de
Title: Prediction of adverse health outcomes in older patients visiting the Emergency
Department: the APOP study
Abstrac
General introduction
1
| 9
General introduction
Older patients experience high rates of adverse health outcomes after visiting the emergency department (ED),[1] but at the moment of acute presentation it is difficult to determine who will deteriorate. Identification of older patients at risk for adverse health outcomes with a screening instrument may be helpful to assist health care professionals to anticipate on the risk of possible deterioration and deliver care accordingly. Several screening instruments have been developed, of which the Identification of Seniors at Risk (ISAR)[2] and Triage Risk Stratification Tool (TRST)[3] are studied most. Usability of such risk stratification screening instruments is debated, due to the limitation in distinguishing low from high risk patients and because a relatively high proportion of patients is incorrectly assigned as ‘high risk’.[4, 5] To date, there still is a lack of pragmatic, accurate and reliable instruments for risk stratification of older patients in the ED.[4]
The rate of adverse health outcomes is particularly high in the first three months after the ED visit. Approximately 10% will die and up to 45% will experience functional decline. [1] A comprehensive geriatric assessment (CGA) is able to identify the older patients at increased risk and consequently improve outcomes.[6] Performing a CGA in the acute setting is virtually impossible, due to the time limitation and often the condition of the patient. Therefore, another strategy is necessary in order to identify those at high risk. A two-step approach is suggested in order to reduce the incidence of adverse health outcomes.[7] First a screening instrument is needed to identify the patients at increased risk. The second step is to target interventions in patients at highest risk. Interventions which are tailored to the individuals’ need and preferences, for example determined with a CGA, can help older patients to maintain independence.[6, 8]
The ED is designed for acutely ill and injured patients and is characterized by a high patient turnover, rapid triage, acute interventions and with a focus on disposition.[1, 9] Since the 1980’s scientists payed increasing attention to the health care needs of the older patients[10] and now in the 21st century the need to redesign the core of the ED is
Chapter 1
10 |
experienced as an unfamiliar noisy environment, while laying on a thin mattress in a room with little privacy, with the physical examinations being quickly performed and often with a restriction on nutrition and drinks.[19]
Multiple factors contribute to the complexity of delivering adequate care to the older patient in the ED.[18, 20] Approximately 20-40% of this population present with impaired cognition, but this is recognised only in a third of the cases.[11, 21-23] Older patients often present with atypical symptoms, resulting in incomplete resolution of their initial complaints.[1] They have a high prevalence of comorbidities, which causes that physicians have to deal with a mixture of chronic, subacute and acute issues.[22, 24, 25] The complex older patients in the ED challenges physicians to deliver adequate (after)care for the individual patient.
General introduction
1
| 11
Outline of the thesis
Chapter 1
12 |
References
1. Aminzadeh, F. and W.B. Dalziel, Older adults in the emergency department: a systematic review
of patterns of use, adverse outcomes, and effectiveness of interventions. Ann.Emerg.Med., 2002.
39 (3) : p. 238-247.
2. McCusker, J., et al., Detection of older people at increased risk of adverse health outcomes after an
emergency visit: the ISAR screening tool. J.Am.Geriatr.Soc., 1999. 47 (10): p. 1229-1237.
3. Meldon, S.W., et al., A brief risk-stratification tool to predict repeat emergency department visits
and hospitalizations in older patients discharged from the emergency department. Acad Emerg
Med, 2003. 10 (3): p. 224-32.
4. Carpenter, C.R., et al., Risk factors and screening instruments to predict adverse outcomes for
undifferentiated older emergency department patients: a systematic review and meta-analysis.
Acad Emerg Med, 2015. 22 (1): p. 1-21.
5. Yao, J.L., et al., A systematic review of the identification of seniors at risk (ISAR) tool for the prediction
of adverse outcome in elderly patients seen in the emergency department. Int J Clin Exp Med, 2015.
8 (4): p. 4778-86.
6. Ellis, G., T. Marshall, and C. Ritchie, Comprehensive geriatric assessment in the emergency
department. Clin Interv Aging, 2014. (9): p. 2033-43.
7. McCusker, J., et al., Rapid two-stage emergency department intervention for seniors: impact on
continuity of care. Acad.Emerg.Med., 2003. 10 (3): p. 233-243.
8. Beswick, A.D., et al., Complex interventions to improve physical function and maintain independent
living in elderly people: a systematic review and meta-analysis. Lancet, 2008. 371 (9614): p. 725-35.
9. Adams, J.G. and L.W. Gerson, A new model for emergency care of geriatric patients. Acad Emerg Med, 2003. 10 (3): p. 271-4.
10. Lowenstein, S.R., et al., Care of the elderly in the emergency department. Ann Emerg Med, 1986. 15 (5): p. 528-35.
11. Samaras, N., et al., Older patients in the emergency department: a review. Ann.Emerg.Med., 2010. 56 (3): p. 261-269.
12. McCusker, J., et al., Determinants of emergency department visits by older adults: a systematic
review. Acad Emerg Med, 2003. 10 (12): p. 1362-70.
13. Gray, L.C., et al., Profiles of older patients in the emergency department: findings from the interRAI
Multinational Emergency Department Study. Ann Emerg Med, 2013. 62 (5): p. 467-74.
14. Gruneir, A., M.J. Silver, and P.A. Rochon, Emergency department use by older adults: a literature
review on trends, appropriateness, and consequences of unmet health care needs. Med Care Res
Rev, 2011. 68 (2): p. 131-55.
15. Sager, M.A., et al., Functional outcomes of acute medical illness and hospitalization in older persons. Arch Intern Med, 1996. 156 (6): p. 645-52.
16. Hastings, S.N., et al., Adverse health outcomes after discharge from the emergency
General introduction
1
| 13
17. de Saint-Hubert, M., et al., Risk factors predicting later functional decline in older hospitalized
patients. Acta Clin.Belg., 2009. 64 (3): p. 187-194.
18. Singal, B.M., et al., Geriatric patient emergency visits. Part I: Comparison of visits by geriatric and
younger patients. Ann Emerg Med, 1992. 21 (7): p. 802-7.
19. Hwang, U. and R.S. Morrison, The geriatric emergency department. J Am Geriatr Soc, 2007. 55 (11): p. 1873-6.
20. Lucke, J.A., et al., Early prediction of hospital admission for emergency department patients: a
comparison between patients younger or older than 70 years. Emerg Med J, 2018. 35 (1): p. 18-27.
21. Litovitz, G.L., et al., Recognition of psychological and cognitive impairments in the emergency
department. Am J Emerg Med, 1985. 3 (5): p. 400-2.
22. Salvi, F., et al., The elderly in the emergency department: a critical review of problems and solutions. Intern.Emerg.Med., 2007. 2 (4): p. 292-301.
23. Schofield, I., et al., Screening for cognitive impairment in older people attending accident and
emergency using the 4-item Abbreviated Mental Test. Eur J Emerg Med, 2010. 17 (6): p. 340-2.
24. Schellevis, F.G., et al., Comorbidity of chronic diseases in general practice. J Clin Epidemiol, 1993. 46 (5): p. 469-73.
25. Barnett, K., et al., Epidemiology of multimorbidity and implications for health care, research, and