Innate and adaptive host responses and their genetic control in tuberculosis : studies in Indonesia, a highly TB endemic setting

Plasma granulysin levels and cellular interferon-γ production correlate with curative host responses in tuberculosis, while plasma interferon-γ levels correlate with

The outcome of mycobacterial infection is partly influenced by host genetic factors that control activation of innate and adaptive immune responses.. There is

Whereas TNF-α production was higher in active-TB patients than in controls, IFN-γ production was strongly depressed during active TB, correlated inversely with TB

In contrast, plasma interferon-γ (IFN-γ) levels were significantly higher in active TB cases than in controls, normalised during treatment and correlated with

We analyzed the distribution of polymorphisms in four essential genes from the IL-12/ IFN- axis, IL12B, IL12RB1, IFNG and IFNGR1, in 382 pulmonary tuberculosis patients and

In this study we have identified genetic variants within three genes of the complement pathway which show significant association with pulmonary TB in an Indonesian

(2004) VDR and NRAMP1 gene polymorphisms in susceptibility to pulmonary tuberculosis among the Chinese Han population: a case-

d Categorized as sputum microscopic examination results at week 8... many diabetic patients as nondiabetic patients had a sputum culture result that was positive for M.