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Cardiovascular magnetic resonance of myocardial viability

Kaandorp, T.A.M.

Citation

Kaandorp, T. A. M. (2007, March 14). Cardiovascular magnetic resonance of myocardial

viability. Department Radiology, Faculty of Medicine / Leiden University Medical Center

(LUMC), Leiden University. Retrieved from https://hdl.handle.net/1887/11409

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the

Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/11409

Note: To cite this publication please use the final published version (if applicable).

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Cardiovascular magnetic resonance

of myocardial viability

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Cardiovascular magnetic resonance

of myocardial viability

Proefschrift ter verkrijging van

de graad van Doctor aan de Universiteit Leiden,

op gezag van Rector Magnificus prof. mr. P. F. van der Heijden, volgens besluit van het College voor Promoties

te verdedigen op woensdag 14 maart 2007 klokke 16:15 uur

door

Theodorus Albertus Maria Kaandorp geboren te Helmond

in 1970

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Promotiecommissie

Promotores: Prof.dr. A. de Roos Prof.dr. J. J. Bax

Prof.dr. E. E. van der W all Copromotor: Dr. H. J. Lamb

Referent: Prof.dr. J. Bogaert

(Katholieke Universiteit Leuven, België)

The research described in this thesis was carried out at the department of Radiology (head: Prof.dr. J. L. Bloem) and the department of Cardiology (head: Prof.dr. E. E.

van der W all) of the Leiden University Medical Center.

NW O Research support 2001: 902-37-124 (Lamb H. J.).

Financial support by the Netherlands Heart Foundation for the publication of this thesis is gratefully acknowledged.

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In herinnering aan mijn vader

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© T. A. M. Kaandorp, Den Haag, The Netherlands. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanic, photocopying, and recording or otherwise, without prior written permission of the author.

ISBN 978-90-855928-6-0

Publication of the thesis was financially supported by Astra Zeneca B.V., Foundation Imago, Guerbet Nederland B.V. and Medis medical imaging systems. Additional financial support is provided by Bouwbedrijf Ceelen B.V., DTC B.V., Rednose B.V., and THS B.V.

Cover design: T. A. M. Kaandorp

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Contents

Chapter 1 General introduction and outline 13

Part I – Technical evaluation

Chapter 2 Magnetic resonance imaging of coronary arteries, the ischemic cascade and myocardial infarction

21

Chapter 3 Quantification of myocardial infarct size and transmurality by delayed contrast-enhanced magnetic resonance imaging in men

41

Chapter 4 Head-to-head comparison between delayed contrast-enhanced magnetic resonance imaging and dobutamine magnetic resonance imaging in male patients with ischemic cardiomyopathy

57

Chapter 5 Which parameters on magnetic resonance imaging determine Q waves on the electrocardiogram?

69

Part II – Clinical application

Chapter 6 Cardiovascular magnetic resonance imaging to assess myocardial viability in chronic ischemic left ventricular dysfunction

87

Chapter 7 Assessment of right ventricular infarction with delayed contrast-enhanced magnetic resonance imaging

107

Chapter 8 Scar tissue on delayed contrast-enhanced magnetic resonance imaging predicts left ventricular remodeling after acute infarction

123

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Contents

Chapter 9 Prediction of beneficial effect of ß-blocker therapy in severe ischemic cardiomyopathy: assessment of global left ventricular ejection fraction using dobutamine stress cardiovascular magnetic resonance imaging

131

Chapter 10 Relation between regional and global systolic function in patients with ischemic cardiomyopathy after ß-blocker therapy or revascularization

139

Chapter 11 Effect of posterolateral scar tissue on clinical and echocardiographic improvement following cardiac resynchronization therapy

157

Chapter 12 Summary Samenvatting List of publications Curriculum vitae

179 182 185 191

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