Cardiovascular magnetic resonance of myocardial viability
Kaandorp, T.A.M.
Citation
Kaandorp, T. A. M. (2007, March 14). Cardiovascular magnetic resonance of myocardial
viability. Department Radiology, Faculty of Medicine / Leiden University Medical Center
(LUMC), Leiden University. Retrieved from https://hdl.handle.net/1887/11409
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the
Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/11409
Note: To cite this publication please use the final published version (if applicable).
Cardiovascular magnetic resonance
of myocardial viability
Cardiovascular magnetic resonance
of myocardial viability
Proefschrift ter verkrijging van
de graad van Doctor aan de Universiteit Leiden,
op gezag van Rector Magnificus prof. mr. P. F. van der Heijden, volgens besluit van het College voor Promoties
te verdedigen op woensdag 14 maart 2007 klokke 16:15 uur
door
Theodorus Albertus Maria Kaandorp geboren te Helmond
in 1970
Promotiecommissie
Promotores: Prof.dr. A. de Roos Prof.dr. J. J. Bax
Prof.dr. E. E. van der W all Copromotor: Dr. H. J. Lamb
Referent: Prof.dr. J. Bogaert
(Katholieke Universiteit Leuven, België)
The research described in this thesis was carried out at the department of Radiology (head: Prof.dr. J. L. Bloem) and the department of Cardiology (head: Prof.dr. E. E.
van der W all) of the Leiden University Medical Center.
NW O Research support 2001: 902-37-124 (Lamb H. J.).
Financial support by the Netherlands Heart Foundation for the publication of this thesis is gratefully acknowledged.
In herinnering aan mijn vader
© T. A. M. Kaandorp, Den Haag, The Netherlands. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanic, photocopying, and recording or otherwise, without prior written permission of the author.
ISBN 978-90-855928-6-0
Publication of the thesis was financially supported by Astra Zeneca B.V., Foundation Imago, Guerbet Nederland B.V. and Medis medical imaging systems. Additional financial support is provided by Bouwbedrijf Ceelen B.V., DTC B.V., Rednose B.V., and THS B.V.
Cover design: T. A. M. Kaandorp
Contents
Chapter 1 General introduction and outline 13
Part I – Technical evaluation
Chapter 2 Magnetic resonance imaging of coronary arteries, the ischemic cascade and myocardial infarction
21
Chapter 3 Quantification of myocardial infarct size and transmurality by delayed contrast-enhanced magnetic resonance imaging in men
41
Chapter 4 Head-to-head comparison between delayed contrast-enhanced magnetic resonance imaging and dobutamine magnetic resonance imaging in male patients with ischemic cardiomyopathy
57
Chapter 5 Which parameters on magnetic resonance imaging determine Q waves on the electrocardiogram?
69
Part II – Clinical application
Chapter 6 Cardiovascular magnetic resonance imaging to assess myocardial viability in chronic ischemic left ventricular dysfunction
87
Chapter 7 Assessment of right ventricular infarction with delayed contrast-enhanced magnetic resonance imaging
107
Chapter 8 Scar tissue on delayed contrast-enhanced magnetic resonance imaging predicts left ventricular remodeling after acute infarction
123
Contents
Chapter 9 Prediction of beneficial effect of ß-blocker therapy in severe ischemic cardiomyopathy: assessment of global left ventricular ejection fraction using dobutamine stress cardiovascular magnetic resonance imaging
131
Chapter 10 Relation between regional and global systolic function in patients with ischemic cardiomyopathy after ß-blocker therapy or revascularization
139
Chapter 11 Effect of posterolateral scar tissue on clinical and echocardiographic improvement following cardiac resynchronization therapy
157
Chapter 12 Summary Samenvatting List of publications Curriculum vitae
179 182 185 191