Single cell biochemistry to visualize antigen presentation and drug resistance Griekspoor, A.C.

In humans, three different proteins facilitate the cell surface presen- tation of antigens to cells of the immune system, each part of a separate antigen presentation

Besides its ligand binding capability, the LBD also plays an important role in nuclear translocation, chaperone binding, receptor dimerization, and coregulator recruitment

The PKA- associated targets outside ER α may well include SRCs, and the effect of PKA-mediated phosphorylation of these cofactors in T47D cells, in which we measured

We applied Fluorescent Resonance Energy Transfer (FRET) to measure an altered orientation between ER α and SRC-1 that was dependent on phos- phorylation of the PKA target

The resulting resistance profile from this study allows us to rank the different available anti- estrogens based on their stringency, and provides a rationale

De MHC klasse II route is alleen operationeel in professio- nele antigeen presenterende cellen en door de cel opgenomen materiaal vormt de bron van antigenen die door deze

Single cell biochemistry to visualize antigen presentation and drug resistance..

Hoewel het gros van de wetenschappelijke artikelen niet langer in gedrukte vorm verschijnt, wordt het concept “specialistisch tijdschrift” door de meeste uitgevers in virtuele