Cover Page
The handle http://hdl.handle.net/1887/49402 holds various files of this Leiden University dissertation.
Author: Lenselink, E.B.
Title: Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands
Issue Date: 2017-06-07
Curriculum Vitae
Bart Lenselink was born on 14 October 1988 in The Hague, Netherlands. He went to Adelbert College in Wassenaar, where he finished gymnasium (biology and health and nature and technology) in 2007. In September 2007 he started his study in Biopharma- ceutical sciences, in which during a minor internship in the third year of the program, he became interested in methods in the context of computer aided drug design. He pursued this path by doing a 9 months internship under supervision of Dr. van Westen and prof.
IJzerman, focusing on proteochemometric modelling applied to class A GPCRs. During his second, 6 months internship, he went to the Andrej Šali lab (UCSF). There he focused on the development and application of peptide docking algorithms.
After his master he got the opportunity to pursue a PhD study under supervision of Prof.
IJzerman and Prof. van Vlijmen. He worked on his PhD from June 2012 to June 2016; most of the research can be found in this thesis. Multiple projects were done in collaboration with Schrödinger, and from May 2014 until August 2014 Bart performed part of his re- search at Schrödinger in New York. Bart presented at multiple international conferences and user group meetings. Moreover he was the winner of the 2015 LACDR PhD compe- tition for his presentation on “Predicting Drug Potency”.
Currently he is a postdoc in a joint project between Janssen Pharmaceutica, UAB (Barce- lona), and Leiden University. This project focuses on the use of advanced computational tools in the context of industrial drug discovery projects.
