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The following handle holds various files of this Leiden University dissertation:

http://hdl.handle.net/1887/59463

Author: Narayen, I.C.

Title: Neonatal screening with pulse oximetry Issue Date: 2017-11-22

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STELLINGEN

1. Adding pulse oximetry to the screening of critical congenital heart defects (CCHD) increases the amount of timely diagnosed CCHD. This thesis

2. The early detection of cardiac and non-cardiac pathology with pulse oximetry screening, has the potential to decrease the morbidity and mortality of newborns. This thesis

3 Following the propositions above, pulse oximetry should be added to the standard assessment of newborns in the first days after birth. This thesis

4. An oxygen saturation less than 95% in a newborn after one hour of life is not within the normal range and clinical evaluation by the caregiver should follow. This thesis

5. The detection rate of critical congenital heart defects at the antenatal anomaly scan (at 20 weeks of gestation) strongly influences the sensitivity of pulse oximetry screening. This thesis 6. Since both pulse oximetry screening and physical examination are not ideal in detecting coarctations of the aorta, other screening strategies for this congenital heart defect should be sought. Riede FT, Neonatology 2012;101:13, modified

7. Clinical assessment of a newborn infants colour with the human eye is unreliable.

O’Donnell CP, Arch Dis Child Fetal Neonatal Ed 2007;92:F465-7, modified

8. Infection is an important cause for mortality in term infants in the Netherlands. Stichting Perinatale Audit Nederland, A terme sterfte 2010-2012

9.Bottom-up implementation is more realistic and practical and much more democratic than the top-down approach. deLeon P, Journal of Public Administration Research and Theory 2002; 12:467-92

10. I have never tried that before, so I think I should definitely be able to do that. Pippi Longstocking, authored by Astrid Lindgren (1907-2002) As a PhD candidate you do things you never did before, and think/hope you will succeed in, such as presenting at international meetings.

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11. Timing and accuracy is really what matters at the end of the day. Carson Wentz, June 9th 2016. Early detection of critical congenital heart defect improves the survival and outcome.

12. Success is only meaningful and enjoyable if it feels like your own. Michelle Obama, June 17th 2012. Even small successes in your own research can feel like a great victory.

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